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Catalytic Site Atlas

CSA LITERATURE entry for 1af7

E.C. nameprotein-glutamate O-methyltransferase
SpeciesSalmonella typhimurium (Bacteria)
E.C. Number (IntEnz) 2.1.1.80
CSA Homologues of 1af71bc5,3g07,
CSA Entries With UniProtID P07801
CSA Entries With EC Number 2.1.1.80
PDBe Entry 1af7
PDBSum Entry 1af7
MACiE Entry 1af7

Literature Report

IntroductionCheR is a methyltransferase involved in methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues. This reaction is important for modulating a bacterium's response to a gradient of attractant or repellent.
MechansimAccording to 2061337, “it was determined that the mechanism of the reaction catalyzed by the enzyme is random.”
Reaction

Catalytic Sites for 1af7

Literature References

Notes:
Shiomi D
Dual recognition of the bacterial chemoreceptor by chemotaxis-specific domains of the CheR methyltransferase.
J Biol Chem 2002 277 42325-42333
PubMed: 12101179
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