Catalytic Site Atlas
Enter a PDB code, UniProKB code or EC number in one of the boxes Below to obtain catalytic residue details from the CSA.
A NEW VERSION OF THE CSA UPDATED 14th November 2013
The Catalytic Site Atlas (CSA) is a database documenting enzyme active sites and catalytic residues in enzymes of 3D structure. We defined a classification of catalytic residues which includes only those residues thought to be directly involved in some aspect of the reaction catalysed by an enzyme.
Each CSA entry lists the catalytic residues found in that entry, using PDB residue numbering. Each site is also marked with an evidence tag, which is either "Literature reference" or "Homologue". If the entry is by sequence comparison you can follow the link to the original entry. The active site can be visualised using a JMol viewer and each catalytic site in the structure can be highlighted and zoomed into by selecting from the drop down list on the left hand side of the viewer as well as further rendering options.
Each entry contains a link to a list of homologous entries found by homology, and a link to other PDB structures with identical E.C. numbers or UniProKB identifier to the entry you are viewing.
A number of people have contributed to the CSA over the years as annotators. We would like to thank Jonathan Barker, Carine Berezin, Amy Buchanan-Huges, Lynn Carr, Olivia Chan, Josephine Charalambous, Emma Compton, Atlanta Cook, Jennifer Dawe, Angelica Datta, Christian Drew, Alex Gutteridge, Stephanie Juniat, Roman Laskowski, Oleg Lenive, Mei Leung, Stuart Lucas, Ben McLeod, Malcolm MacArthur, Gary McDowell, Angela Malumbe, Duncan Milburn, Fiona Morgan, James Murray, Nozomi Nagano, Jonathan Ng, Emma Penn, Craig Porter, Judith Reeks, Peter Sarkies, Steven Smith, James Torrance, Annabel Todd, Andrew Wallace, Anna Waters, Sophie Williams, and Eleanor Wright.