DNA & RNA

Popular services

Ensembl

Ensembl enables and advances genome science by providing high-quality, integrated annotation on vertebrate genomes within a consistent and accessible infrastructure.

Ensembl Genomes

An integrating portal for genome-scale data from non-veterbrate species.

European Nucleotide Archive

A comprehensive archive of submitted nucleotide sequence read, assembly and functional annotation data

1000 Genomes

A deep catalog of shared human genetic variation in population groups worldwide.

Clustal Omega

A new multiple sequence alignment tool using HMM-HMM profiles, suitable for medium-large alignments.

Clustal Phylogeny

Commonly used phylogenetic tree generation methods provided by the ClustalW2 program.

European Genome-phenome Archive

A service for permanent archiving and sharing of all types of potentially identifiable genetic, molecular and phenotypic data resulting from biomedical research projects.

EBI Metagenomics

A resource for the analysis and archiving of metagenomic data.

All services

1000 Genomes

A deep catalog of shared human genetic variation in population groups worldwide.

CENSOR

A tool that screens query sequences against a reference collection of repeats.

Clustal Omega

A new multiple sequence alignment tool using HMM-HMM profiles, suitable for medium-large alignments.

Clustal Phylogeny

Commonly used phylogenetic tree generation methods provided by the ClustalW2 program.

ClustalW2

Multiple sequence alignment with ClustalW2.

Database of Genomic Variants archive

A repository that provides archiving, accessioning and distribution of publicly available genomic structural variants, in all species.

EBI Metagenomics

A resource for the analysis and archiving of metagenomic data.

EMBOSS Tools

Selected EMBOSS tools for sequence analysis, providing: pairwise sequence alignment, sequence format conversion, sequence translation and back-translation, and sequence statistics.

ENA/SVA - Sequence Version Archive

Historical repository of EMBL-Bank entries

Ensembl

Ensembl enables and advances genome science by providing high-quality, integrated annotation on vertebrate genomes within a consistent and accessible infrastructure.

Ensembl Genomes

An integrating portal for genome-scale data from non-veterbrate species.

European Genome-phenome Archive

A service for permanent archiving and sharing of all types of potentially identifiable genetic, molecular and phenotypic data resulting from biomedical research projects.

European Nucleotide Archive

A comprehensive archive of submitted nucleotide sequence read, assembly and functional annotation data

FASTA [nucleotide]

Similarity search tool for nucleotide sequence databases.

FASTM [nucleotide]

Nucleotide fragment similarity search tool

GeneWise

Compare a protein sequence to a genomic DNA sequence.

GGSEARCH [nucleotide]

Optimal global similarity search tool to search nucleotide databases for sequences homologous to your query.

GLSEARCH [nucleotide]

Optimal global-query, local-database, similarity search tool to search nucleotide databases for sequences homologous to your query.

HUGO Gene Nomenclature Committee

A database of approved gene symbols, names and associated data for human genes and their vertebrate orthologs.

IMGT/HLA

The IMGT/HLA Database provides a specialist database for sequences of the human major histocompatibility complex (HLA) and includes the official sequences for the WHO Nomenclature Committee For Factors of the HLA System.

Kalign

Very fast multiple sequence alignment tool, suitable for large alignments.

LALIGN [nucleotide]

LALIGN finds internal duplications by calculating non-intersecting local alignments of protein or nucleotide sequences.

MAFFT

Multiple sequence alignment tool that uses Fast Fourier Transforms, suitable for medium alignments.

MUSCLE

Accurate multiple sequence alignment tool, especially good with proteins. Suitable for medium alignments.

MView

Transform a sequence similarity search result into a multiple sequence alignment or reformat a multiple sequence alignment.

NCBI BLAST [nucleotide]

Fast local similarity search tool for nucleotide sequence databases.

Patent databases

Non-redundant patent sequence databases providing access to full-text patent documents.

PromoterWise

PromoterWise compares two DNA sequences allowing for inversions and translocations, ideal for promoters.

Readseq

Conversion between common biological sequence formats.

Rfam

A database of covariance models and alignments to describe non-coding RNA families.

Sequence Checksum Generator

Generation of checksums for protein and nucleotide sequences.

SRS - Sequence Retrieval System

Advanced querying of EMBL-EBI databases.

SSEARCH [nucleotide]

Smith-Waterman sequence similarity search against nucleotide databases.

T-Coffee

Consistency-based multiple sequence alignment tool that attempts to mitigate the pitfalls of progressive alignment methods. Suitable for small alignments.

TreeFam

A database of phylogenetic trees of animal species to provide orthologue/paralogue definitions.

Web Services

Programmatic access to various data resources and analysis tools via Web Services technologies.

WU-BLAST [nucleotide]

Sequence similarity search of nucleotide databases using WU-BLAST.