Search for O89023

Term identified:
O89023
Classification:
house mouse
Mus musculus

Gene

Tripeptidyl peptidase I

Gene Information and Sequence
Variations
Orthologues
Paralogues
  • Tpp1 has no paralogues in Ensembl
Regulation
  • The Ensembl project produces genome databases for vertebrates and other eukaryotic species, and makes this information freely available online.
  • The current release 76 ( August 2014 ) of the Ensembl provides access to the genomic, comparative, functional and variation data from 68 species.
  • View more information in Ensembl.

Expression

Tpp1 expression summary

organism part
  • Not studied or no differential expression found for this gene
  • View all
disease
  • Not studied or no differential expression found for this gene
  • View all
cell type
  • Not studied or no differential expression found for this gene
  • View all
cell line
  • Not studied or no differential expression found for this gene
  • View all
Compound treatment
  • estradiol, dibenzazepine 10 micromoles per kilogram, cAMP
  • View all
developmental stage
  • Not studied or no differential expression found for this gene
  • View all
Infection
  • Not studied or no differential expression found for this gene
  • View all
phenotype
  • Not studied or no differential expression found for this gene
  • View all
  • Data source: Expression Atlas (12-11-2013).
  • Expression Atlas is a semantically enriched database of publicly available gene and transcript expression data. The data is re-analysed in-house to detect genes showing interesting baseline and differential expression patterns under the conditions of the original experiment.
  • About Expression Atlas

Protein

Tripeptidyl-peptidase 1

Function
  • Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus
Subcellular Location
  • Lysosome. Melanosome (By similarity)
GO Cellular Components
GO Biological Processes
GO Molecular Functions
Protein Existence
  • Evidence at protein level
Isoform
  • No isoforms available
Sequence
  • UniProt Data Source, 2014.08
  • UniProt is a comprehensive, high-quality and freely accessible resource for protein sequences and functional information.
  • View more information in UniProt

Protein Structure

No protein structure references have been found

Literature

These articles contain the gene or protein name in the title, abstract or keyword. They are ordered by date of publication with the most recent first. Citations are supported by CiteXplore, which includes all of PubMed (updated daily), Agricola, patents, PubMed Central and a selection of biomedical theses and reports.
All Articles (189)

  1. Katz ML, Coates JR, Sibigtroth CM, Taylor JD, Carpentier M, Young WM, Wininger FA, Kennedy D, Vuillemenot BR and O'Neill CA
    Journal of neuroscience research 92(11) Nov 2014
  2. Sexton AN, Regalado SG, Lai CS, Cost GJ, O'Neil CM, Urnov FD, Gregory PD, Jaenisch R, Collins K and Hockemeyer D
    Genes & development 28(17) Sep 2014
  3. Karlseder J
    Genes & development 28(17) Sep 2014
View all 189 in Europe PubMed Central

These articles are reviews only. They have been selected because they have the gene or protein name in the title, abstract or keyword. They are ordered by date of publication with the most recent first. Citations are supported by CiteXplore, which includes all of PubMed (updated daily), Agricola, patents, PubMed Central and a selection of biomedical theses and reports.
Reviews (18)

  1. Rajavel M, Mullins MR and Taylor DJ
    Biochimica et biophysica acta 1844(9) Sep 2014
  2. Gramatges MM and Bertuch AA
    Translational research : the journal of laboratory and clinical medicine 162(6) Dec 2013
  3. Anderson GW, Goebel HH and Simonati A
    Biochimica et biophysica acta 1832(11) Nov 2013
View all 18 in Europe PubMed Central

These articles contain the gene or protein name in the title. They are ordered by publication date, with the most recent first. Citations are supported by CiteXplore, which includes all of PubMed (updated daily), Agricola, patents, PubMed Central and a selection of biomedical theses and reports.
Title Contains "Tpp1" (52)

  1. Sexton AN, Regalado SG, Lai CS, Cost GJ, O'Neil CM, Urnov FD, Gregory PD, Jaenisch R, Collins K and Hockemeyer D
    Genes & development 28(17) Sep 2014
  2. Karlseder J
    Genes & development 28(17) Sep 2014
  3. Rajavel M, Mullins MR and Taylor DJ
    Biochimica et biophysica acta 1844(9) Sep 2014
View all 52 in Europe PubMed Central

These articles are supplied by UK PubMed Central and are free to access from anywhere in the world. They have been selected because they have the gene or protein name in the title, abstract or keyword. They are ordered by date of publication with the most recent first. Citations are supported by CiteXplore, which includes all of PubMed (updated daily), Agricola, patents, PubMed Central and a selection of biomedical theses and reports.
Free Full Text Articles (85)

  1. Armstrong CA, Pearson SR, Amelina H, Moiseeva V and Tomita K
    Current biology : CB 24(17) Sep 2014
  2. Ray S, Bandaria JN, Qureshi MH, Yildiz A and Balci H
    Proceedings of the National Academy of Sciences of the United States of America 111(8) Feb 2014
  3. Jones M, Osawa G, Regal JA, Weinberg DN, Taggart J, Kocak H, Friedman A, Ferguson DO, Keegan CE and Maillard I
    The Journal of clinical investigation 124(1) Jan 2014
View all 85 in Europe PubMed Central

This section lists patents that mention the gene or the protein. They come from the European Patent Office (EPO), but coverage extends to USA and world-wide patents.
Patents (1)

  1. ZUMARRAGA URIBESALGO MIREN, DOMINGUEZ HORMAETXE SAIOA, MARTINEZ MARTINEZ ANTONIO, SIMON BUELA LAUREANO, NAGORE CASAS DANIEL and HORMAECHE BERCIANO ITSASO
    PROTEOMIKA S L 11 Feb 2010
View in Europe PubMed Central

These articles have been selected by curators of gene and protein databases such as UniProt. If your search found a hit in UniProt, then the reference list from that record is displayed below
Curator-Selected Articles for "Tpp1" (23)

  1. Micsenyi MC, Sikora J, Stephney G, Dobrenis K and Walkley SU
    The Journal of neuroscience : the official journal of the Society for Neuroscience 33(26) Jun 2013
  2. Meng Y, Sohar I, Wang L, Sleat DE and Lobel P
    PloS one 7(7) 2012
  3. Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G and Ballabio A
    PLoS biology 9(1) 2011
View all 23 in Europe PubMed Central
  • Europe PubMed Central is a database of over 28 million citations, incorporating PubMed, Agricola, and Patent information, and over 2.6 million full text research articles, of which 570K are Open Access. It is updated daily, and is enriched by text-mined terms, links to databases at the EBI, as well as information on who is citing who in the biomedical literature.
  • Europe PubMed Central