RHEA:10656

S-adenosyl-L-methionine + guanidinoacetate <?> S-adenosyl-L-homocysteine + creatine + H+

Last modified: 2012-07-10. Chemically balanced: yes.

S-adenosyl-L-methionine
Name origin: UniProt - CHECKED (C)
CHEBI:59789
Formula: C15H23N6O5S
Charge: 1
ChEBI compound status: CHECKED (C)
(No structure available)
+
guanidinoacetate
Name origin: UniProt - CHECKED (C)
CHEBI:57742
Formula: C3H7N3O2
Charge: 0
ChEBI compound status: CHECKED (C)
(No structure available)
<?>
S-adenosyl-L-homocysteine
Name origin: UniProt - CHECKED (C)
CHEBI:57856
Formula: C14H20N6O5S
Charge: 0
ChEBI compound status: CHECKED (C)
(No structure available)
+
creatine
Name origin: UniProt - CHECKED (C)
CHEBI:57947
Formula: C4H9N3O2
Charge: 0
ChEBI compound status: CHECKED (C)
(No structure available)
+
H+
Name origin: UniProt - CHECKED (C)
CHEBI:15378
Formula: H
Charge: 1
ChEBI compound status: CHECKED (C)
(No structure available)

Same participants, different directions

  • RHEA:10657 S-adenosyl-L-methionine + guanidinoacetate => S-adenosyl-L-homocysteine + creatine + H+
  • RHEA:10658 S-adenosyl-L-homocysteine + creatine + H+ => S-adenosyl-L-methionine + guanidinoacetate
  • RHEA:10659 S-adenosyl-L-methionine + guanidinoacetate <=> S-adenosyl-L-homocysteine + creatine + H+

Cross references

Reactions and Pathways (5)
UniPathway: Database of manually curated metabolic pathways, whose primary goal is to describe the metabolic data of UniProtKB/Swiss-Prot Database entries.
KEGG reaction: Knowledge base for biochemical reactions by the Kyoto Encyclopedia of Genes and Genomes.
MetaCyc: Database of nonredundant, experimentally elucidated metabolic pathways.
Reactome: A curated knowledgebase of biological pathways.
Enzymes (1)
IntEnz: (Integrated relational Enzyme database) A freely available resource focused on enzyme nomenclature.
Proteins (8)
UniProt: The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation.

Citations

  1. Komoto J, Huang Y, Takata Y, Yamada T, Konishi K, Ogawa H, Gomi T, Fujioka M, Takusagawa F (2002)
    Crystal structure of guanidinoacetate methyltransferase from rat liver: a model structure of protein arginine methyltransferase.
    Journal of molecular biology 320, 223-235 [12079381]
  2. Komoto J, Yamada T, Takata Y, Konishi K, Ogawa H, Gomi T, Fujioka M, Takusagawa F (2004)
    Catalytic mechanism of guanidinoacetate methyltransferase: crystal structures of guanidinoacetate methyltransferase ternary complexes.
    Biochemistry 43, 14385-14394 [15533043]