TitleLigSearch: a knowledge-based web server to identify likely ligands for a protein target
Publication TypeJournal Article
Year of Publication2013
Authorsde Beer TAP, Laskowski RA, Duban M-E, Chan AWE, Anderson WF, Thornton JM
JournalActa Crystallographica Section D
Volume69
Pagination2395-2402
Keywordsligand prediction, LigSearch
AbstractIdentifying which ligands might bind to a protein before crystallization trials could provide a significant saving in time and resources. LigSearch, a web server aimed at predicting ligands that might bind to and stabilize a given protein, has been developed. Using a protein sequence and/or structure, the system searches against a variety of databases, combining available knowledge, and provides a clustered and ranked output of possible ligands. LigSearch can be accessed at http://www.ebi.ac.uk/thornton-srv/databases/LigSearch .
DOI10.1107/S0907444913022294