Protein Data Bank in Europe - Research
The Protein Data Bank in Europe (PDBe) is the European partner in the Worldwide Protein Data Bank organisation (wwPDB), which maintains the single international archive for biomacromolecular structure data. The other wwPDB partners are the Research Collaboratory for Structural Bioinformatics (RCSB) and Biological Magnetic Resonance Bank (BMRB) in the USA and the Protein Data Bank of Japan (PDBj). PDBe is a deposition and annotation site for the Protein Data Bank (PDB) and the Electron Microscopy Data Bank (EMDB).
The major goal of PDBe is to provide integrated structural data resources that evolve with the needs of biologists. To that end, our team endeavours to: handle deposition and annotation of structural data expertly; provide an integrated resource of high-quality macromolecular structures and related data; and maintain in-house expertise in all the major structure-determination techniques (X-ray crystallography, Nuclear Magnetic Resonance spectroscopy and 3D Electron Microscopy). Our specific focus areas are: advanced services, ligands, integration, validation and experimental data.
To transform the structural archives into a truly useful resource for biomedical and related disciplines, we focus our developments on five key areas: advanced services (e.g. PDBePISA, PDBeFold, PDBeMotif and the new PDB browsers); annotation, validation and visualisation of ligand data; integration with other biological and chemical data resources; validation and presentation of information about the quality and reliability of structural data; and exposing experimental data in ways that help all users understand the extent to which they support the structural models and inferences.