International PhD Programme research topics
When you apply for the EMBL International PhD Programme, you are asked to select two EMBL research groups and to indicate up to four research areas that interest you. A variety of backgrounds - such as biology, chemistry, computational science, mathematics and statistics - are relevant to PhD projects at EMBL-EBI. As well as purely computational projects, there may also be possibilities to incorporate some experimental biology in collaborating laboratories.
Here, we show a provisional list of available PhD projects at EMBL-EBI which are available during the Summer recruitment 2015 round.
Summer recruitment 2015 is now closed.
Spring recruitment 2016 will open later this year.
Evolution of Cellular Networks
Dr Pedro Beltrao's group seeks to understand the function and evolution of cellular networks by exploring how genetic variability is propagated through molecules, structures and interaction networks to give rise to phenotypic variability. The group focuses on two areas: the evolution of chemical--genetic interactions in different species and individuals; and the function and evolution of post-translational regulatory networks. There is a strong emphasis in collaborating with experimental groups both for data acquisition and follow-up studies.
Contact Beltrao research group
Led by Dr Alvis Brazma, the Functional Genomics team focuses on providing bioinformatics services and conducting research in gene expression and high-throughput sequencing applications to functional genomics. The team participates in software development related to biomedical informatics and systems microscopy, and is responsible for the Gene Expression Atlas, which encompasses transcriptomics and proteomics. Together with the Sarkans and Petryszak teams, the Functional Genomics team works on the ArrayExpress Archive of Functional Genomics Data, Expression Atlas and the BioStudies Database. Students in the team focus on data analysis and developing new methods and algorithms, integration of data across multiple platforms and types of data. The team is a major contributor to EMBL-EBI's training in transcriptomics and the use of EMBL-EBI tools.
Contact Brazma team
Statistical genomics and systems genetics
Dr Oliver Stegle's research group uses computational approaches to unravel the genotype--phenotype map on a genome-wide scale. Their work focuses on the development and use of statistical methodology to dissect the causes of molecular variation. The group has shown how comprehensive modelling can greatly improve the statistical power to find genetic associations with gene expression levels and provide for an enhanced interpretation of the interplay between genetic variation, transcriptional regulation and molecular traits. The address these methodological questions in the context of close collaborations with experimental groups, where they apply novel statistical tools to study molecular traits in model organisms, plant systems and biomedical applications.
Contact Stegle research group
Gerstung research group (from Aug 2015)
Computational cancer biology
Dr Moritz Gerstung will start a new research group at EMBL-EBI in Aug 2015. Research interests of the Gerstung group cover many aspects of cancer genomics, including evolutionary dynamics, genotype-phenotype associations and clinical applications. The ultimate aim is to understand the complex forces driving cancer and to develop methods for utilising this information in the clinic. The group's research will be part of local collaborations and international consortia such as the International Cancer Genome Consortium.
Contact Research office