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Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics
Species: Homo sapiens (Human)
Project description: We developed a motif-based isotopic quantitative method for dete (More)
Made public: 2015-03-30
Label-free analysis of HCV-associated hepatic fibrosis
Species: Homo sapiens (Human)
Project description: A differential label-fee proteomics approach was performed using (More)
Made public: 2015-03-30
Quantifying histone PTMs by bottom-up MS
Species: Homo sapiens (Human)
Project description: Histone post-translational modifications (PTMs) contribute to ch (More)
Made public: 2015-03-27
Proteomic Analysis of Human Liver S9 Fraction by 2D-LC-MSMS
Species: Homo sapiens (Human)
Project description: proteins identified in human liver S9 fraction. (More)
Made public: 2015-03-26
Proteomic Analysis of Human Liver Microsomes by 2D-LC-MSMS
Species: Homo sapiens (Human)
Project description: proteins identified in human liver microsomes. (More)
Made public: 2015-03-26
Intensity-based label-free proteomics using a quadrupole orbitrap mass spectrometer
Species: Homo sapiens (Human)
Project description: We present a unique data set for benchmarking label free quantit (More)
Made public: 2015-03-25
Analysis of the Candida albicans phosphoproteome
Species: Candida albicans (Yeast)
Project description: Candida albicans is an important human fungal pathogen in both immunocompetent and (More)
Made public: 2015-03-25
Hsp90 inhibition induces both protein-specific and global changes in the ubiquitinome
Species: Homo sapiens (Human)
Project description: protein sites modified with a Gly-Gly motif, the remnant of ubiquitination, in human T-cells treated with (More)
Made public: 2015-03-19
Histone deacetylase inhibitors cause the selective depletion of bromodomain containing proteins
Species: Homo sapiens (Human)
Project description: Histone deacetylases (HDACs) and acetyltransferases control the (More)
Made public: 2015-03-18
Quantitative proteomic analysis of large and small extracellular vesicles from prostate cancer cells
Species: Homo sapiens (Human)
Project description: Extracellular vesicles (EVs) are membranous structures of variab (More)
Made public: 2015-03-18
Simulated phosphopeptide spectral library for confident site localization
Species: Homo sapiens (Human)
Project description: We have developed a new workflow to unambiguously localize phosp (More)
Made public: 2015-03-17
Phosphoproteome characterization of Sendai-virus infection in human epithelial cells
Species: Homo sapiens (Human)
Project description: phosphorylation events during Sendai virus infection in human lung epithelial cells. (More)
Made public: 2015-03-17
SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage
Species: Homo sapiens (Human)
Project description: Small Ubiquitin-like Modifiers play critical roles in the DNA Da (More)
Made public: 2015-03-16
System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel SUMO target proteins and acceptor lysines relevant for genome stability
Species: Homo sapiens (Human)
Project description: regulated by replication stress in human cells. The developed methodology enabled single step purification (More)
Made public: 2015-03-12
Interactome analysis of PYHIN immune regulators
Species: Homo sapiens (Human)
Project description: The human PYHIN proteins, AIM2, IFI16, IFIX, and MNDA, are regulators of immune response (More)
Made public: 2015-03-12
Identification of cytoplasmic proteins interacting with unliganded estrogen receptor α and β- in human breast cancer cells
Species: Homo sapiens (Human)
Project description: Estrogen Receptor subtypes (ERα and ERβ) are transcription facto (More)
Made public: 2015-03-11
Melanoma NRAS
Species: Homo sapiens (Human)
Project description: In the present work we propose a new therapy for NRAS mutant mel (More)
Made public: 2015-03-11
HA-mSLX4 wild type and SIMdependent interactors
Species: Homo sapiens (Human)
Project description: SUMOylation is known to play important roles in the DNA damage r (More)
Made public: 2015-03-02
Direct evidence of milk consumption from ancient human dental calculus, UK
Species: Homo sapiens (Human)
Project description: human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia (More)
Made public: 2015-02-26
Direct evidence of milk consumption from ancient human dental calculus, northern southwest Asia
Species: Homo sapiens (Human)
Project description: human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia (More)
Made public: 2015-02-26
Enrichment or depletion? The impact of stool pretreatment on metaproteomic characterization of the human gut microbiota
Species: Homo sapiens (Human)
Project description: Up to date, most metaproteomic studies of the gut microbiota des (More)
Made public: 2015-02-25
Direct evidence of milk consumption from ancient human dental calculus, northern Europe
Species: Homo sapiens (Human)
Project description: human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia (More)
Made public: 2015-02-25
Direct evidence of milk consumption from ancient human dental calculus, central Europe
Species: Homo sapiens (Human)
Project description: human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia (More)
Made public: 2015-02-25
Direct evidence of milk consumption from ancient human dental calculus, St Helena
Species: Homo sapiens (Human)
Project description: human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia (More)
Made public: 2015-02-25
ERLIC-based strategies for combined quantitative proteome and phosphoproteome analysis with limited sample amounts
Species: Homo sapiens (Human)
Project description: The study aims the development of a sensitive strategy for combi (More)
Made public: 2015-02-25
Proteomics of muscle chronological ageing in post-menopausal women
Species: Homo sapiens (Human)
Project description: molecular mechanisms underlying muscle chronological ageing in human, we have undertaken a top-down (More)
Made public: 2015-02-19
A Metaproteomics Approach to Elucidate Host and Pathogen Protein Expression during Catheter-Associated Urinary Tract Infections
Species: Homo sapiens (Human)
Project description: elucidate the interplay between bacterial virulence and the human immune system within the urine. To this (More)
Made public: 2015-02-17
Unraveling Lysine Deacetylase Inhibitor Specificities for Endogenous Acetylation Sites
Species: Homo sapiens (Human)
Project description: Lysine deacetylases (KDACs) are important regulators of biologic (More)
Made public: 2015-02-16
Fast Profiling of Protease Specificity reveals similar substrate specificities for cathepsins K, L and S
Species: Homo sapiens (Human)
Project description: N-terminal COFRADIC analysis of cathespine K, L and S to obtain (More)
Made public: 2015-02-10
Proteomic profiling of cathepsin specificity by FPPS
Species: Homo sapiens (Human)
Project description: Identification of protease substrates and determination of their (More)
Made public: 2015-02-10
Interaction of cGMP-dependent protein kinase and HAP1
Species: Homo sapiens (Human)
Project description: Here, we use cAMP-based chemical proteomics approach, employing (More)
Made public: 2015-02-09
PCT-SWATH kidney tissues
Species: Homo sapiens (Human)
Project description: DDA and SWATH analysis of human kidney tissues. Data set used for PCT-SWATH paper. PCT-SWATH (More)
Made public: 2015-02-04
Compartment resolved reference map from highly purified naive, activated, effector and memory CD8+ cells
Species: Mus musculus (Mouse)
Project description: . Using LC-MS/MS analysis, identified peptides were matched to human peptides/proteins (SwissProt (More)
Made public: 2015-02-04
SIM-XL: a powerful and user-friendly tool for peptide cross-linking analysis
Species: Homo sapiens (Human)
Project description: sensitive and faster than a competing tool when analyzing a dataset obtained from the human HSP90. The (More)
Made public: 2015-02-02
TurboRAW2MGF: Removing isobaric-related ions improves the peptide/protein identification
Species: Homo sapiens (Human)
Project description: Isobaric labelling technique coupled with high resolution mass s (More)
Made public: 2015-01-30
Identifying novel targets of oncogenic EGF receptor signaling in lung cancer through global phosphoproteomics
Species: Homo sapiens (Human)
Project description: Mutations in the epidermal growth factor receptor (EGFR) kinase (More)
Made public: 2015-01-30
Human Cardiac Stem Cells Receptome
Species: Homo sapiens (Human)
Project description: Human cardiac stem cells (hCSC) express a portfolio of plasma membrane receptors that are involved (More)
Made public: 2015-01-30
Proteomic characterisation of microtubule-dependent modulation of adhesion complexes
Species: Homo sapiens (Human)
Project description: Investigating the effect of microtubule disruption by nocodazole (More)
Made public: 2015-01-30
YBX1 interacting protein
Species: Homo sapiens (Human)
Project description: The Y-box-binding protein 1 (YBX1) plays a critical role in tumo (More)
Made public: 2015-01-30
Human testicular matrix
Species: Homo sapiens (Human)
Project description: ITo derive a scaffold from human testis for the purpose of tissue engineering and regenerative (More)
Made public: 2015-01-30
Phospho-iTRAQ
Species: Homo sapiens (Human)
Project description: One of the most extensively studied protein modifications is pho (More)
Made public: 2015-01-30
iTRAQ-based quantitative proteomics analysis of human HNSCC cells
Species: Homo sapiens (Human)
Project description: Head and neck squamous cell carcinoma (HNSCC) is the sixth most (More)
Made public: 2015-01-29
A role for CPT1A to prevent blood vessel permeability revealed by in depth proteomics
Species: Homo sapiens (Human)
Project description: Endothelial cells (ECs) line the inner wall of blood vessels and (More)
Made public: 2015-01-28
Human brain phosphoproteome analyzed by refined phosphopeptide enrichment and high resolution LC-MS/MS
Species: Homo sapiens (Human)
Project description: of dissecting phosphoproteome in a limited amount of postmortem human brain. (More)
Made public: 2015-01-28
PROMIS-Quan: a novel proteomic method for plasma biomarker quantification
Species: Homo sapiens (Human)
Project description: Unbiased proteomic analysis of plasma samples holds the promise (More)
Made public: 2015-01-28
Proteomic analysis of integrin activation-state-dependent adhesion complexes
Species: Homo sapiens (Human)
Project description: (version 2.2.2; Matrix Science). Peak list files were searched against the IPI Human database (version 3.70 (More)
Made public: 2015-01-26
Quantitative comparison of CSF proteins from T. b. gambiense and T. b. rhodesiense HAT patients
Species: Homo sapiens (Human)
Project description: .) gambiense or T. b. rhodesiense parasites, the causing agent of human African trypanosomiasis (HAT), is a (More)
Made public: 2015-01-23
DIA-Umpire: comprehensive computational framework for data independent acquisition proteomics
Species: Homo sapiens (Human)
Project description: This dataset consists of 44 raw MS files, comprising 27 DIA (SWA (More)
Made public: 2015-01-21
Phosphoproteome dynamics in onset and maintenance of Oncogene-Induced Senescence, proteome dataset
Species: Homo sapiens (Human)
Project description: Expression of the BRAFV600E oncoprotein is known to cause benign (More)
Made public: 2015-01-13
Phosphoproteome dynamics in onset and maintenance of Oncogene-Induced Senescence, phosphoproteome dataset
Species: Homo sapiens (Human)
Project description: Expression of the BRAFV600E oncoprotein is known to cause benign (More)
Made public: 2015-01-12
Mass spectrometry of HLA-I peptidomes reveals strong effects of protein abundance and turnover on antigen presentation
Species: Homo sapiens (Human)
Project description: HLA class I molecules reflect the health state of cells to cytot (More)
Made public: 2015-01-12
A Cell-based Systems Biology Assessment of Human Blood to Monitor Immune Responses After Influenza Vaccination
Species: Homo sapiens (Human)
Project description: mononuclear cells (PBMC) to monitor the immune response after vaccination. Because human blood is comprised (More)
Made public: 2015-01-08
Benchmarking label-free quantification based on data-independent acquisition (DIA) workflows
Species: Homo sapiens (Human)
Project description: Label-free quantification based on data-independent acquisition (More)
Made public: 2015-01-07
A Themis:SHP complex promotes T cell survival
Species: Homo sapiens (Human)
Project description: THEMIS is critical for conventional T cell development but its p (More)
Made public: 2015-01-07
A High-resolution Systems-wide Screen for Substrates of the SCFβTrCP Ubiquitin Ligase - reproducibility evaluation
Species: Homo sapiens (Human)
Project description: This project demonstrates a combined bioinformatics and affinity (More)
Made public: 2015-01-06
A High-resolution Systems-wide Screen for Substrates of the SCFβTrCP Ubiquitin Ligase
Species: Homo sapiens (Human)
Project description: This project demonstrates a combined bioinformatics and affinity (More)
Made public: 2015-01-06
Proteomic analysis uncover a new function and mode of action for mDia2
Species: Homo sapiens (Human)
Project description: mDia2 is an auto-inhibited Formin influencing actin dynamics upo (More)
Made public: 2015-01-06
AP-MS analysis of sirtuin-4 interactions in human fibroblasts
Species: Homo sapiens (Human)
Project description: SIRT4, we used proteomics to define its mitochondrial protein interactions in human fibroblasts. (More)
Made public: 2015-01-05
A quantitative proteomics tool to identify DNA-protein interactions in primary cells or blood
Species: Homo sapiens (Human)
Project description: cells (PBMCs) freshly isolated from human donors. We show that the same DNA sequence binds different (More)
Made public: 2015-01-05
Method to identify novel proteoform peptides from salivary supernatant.
Species: Homo sapiens (Human)
Project description: We describe the use Galaxy framework to facilitate complete prot (More)
Made public: 2015-01-05
Quantitative variability of 342 plasma proteins in a human twin population
Species: Homo sapiens (Human)
Project description: The human plasma proteome is clinically highly significant and has been studied extensively because (More)
Made public: 2015-01-05
Quantitative proteomics of the Neisseria gonorrhoeae cell envelope and membrane vesicles
Species: Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Project description: Neisseria gonorrhoeae (GC) is a human-specific pathogen, and the agent of a sexually transmitted (More)
Made public: 2014-12-19
Proteomics and phosphoproteomics analysis of melanoma BRAF
Species: Homo sapiens (Human)
Project description: Proteomics and phosphosproteomics analysis of BRAF mutant cells. (More)
Made public: 2014-12-19
The E. coli effector EspJ blocks Src kinase activity via amidation and ADP-ribosylation
Species: Homo sapiens (Human)
Project description: In vitro ADP-ribosylated Src-K295M was separated by SDS-PAGE and (More)
Made public: 2014-12-19
Impact of Regulatory Variation from RNA to Protein
Species: Homo sapiens (Human)
Project description: Genetic variants that impact gene regulation are important contributors to human phenotypic (More)
Made public: 2014-12-19
Comprehensive Identification of Phosphorylation Sites on the Numb Endocytic Adaptor Protein
Species: Homo sapiens (Human)
Project description: Numb is an endocytic adaptor protein that functions in the endoc (More)
Made public: 2014-12-16
Characterization of LysargiNase for use in phosphoproteomics experiments, part 1
Species: Homo sapiens (Human)
Project description: Use of parallel digest with LysargiNase (former name: ulilysin) (More)
Made public: 2014-12-16
Characterization of LysargiNase for use in phosphoproteomics experiments, partII
Species: Homo sapiens (Human)
Project description: Use of parallel digest with LysargiNase and trypsin to cover com (More)
Made public: 2014-12-16
LysargiNase and tryptic digest of MDA-MB 231 cell lysates
Species: Homo sapiens (Human)
Project description: Comparison of peptide properties in proteomes digested with Lysa (More)
Made public: 2014-12-16
Metaproteomics of Premature Infant Gut Colonization
Species: Homo sapiens (Human)
Project description: Microbial colonization of the human gastrointestinal tract plays an important role in establishing (More)
Made public: 2014-12-16
N-linked glycoproteome of human seminal plasma
Species: Homo sapiens (Human)
Project description: . Consistent composition of N-linked glycoproteins in human seminal plasma provides evidences that seminal (More)
Made public: 2014-12-15
Absolute protein quantification allows differentiation of cell specific metabolic routes and functions
Species: Homo sapiens (Human)
Project description: , and of human plasma, erythrocytes, and tumor cells lines. We show that the TPA based quantitative data (More)
Made public: 2014-12-15
Combining solid phase extraction with ultra-short gradients in LC-MS/MS substantially improves protein identification per unit of time
Species: Homo sapiens (Human)
Project description: Here, we describe a novel LC system enabling rapid protein/prote (More)
Made public: 2014-12-12
The role of PRDX1 in chemoresistance
Species: Homo sapiens (Human)
Project description: The role of peroxiredoxin 1 in confering chemoresistance in glio (More)
Made public: 2014-12-12
Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells
Species: Homo sapiens (Human)
Project description: (Small Ubiquitin-like Modifier) polypeptides to specific lysine residues in the target protein. In human (More)
Made public: 2014-12-09
Off-target responses in the HeLa proteome subsequent to transient plasmid transfection using SILAC
Species: Homo sapiens (Human)
Project description: We report a significant differential expression of proteins, al (More)
Made public: 2014-12-08
Different Binding Motifs of the Celiac Disease Associated HLA Molecules DQ2.5, DQ2.2 and DQ7.5 Revealed by Relative Quantitative Proteomics of Endogenous Peptide Repertoires
Species: Homo sapiens (Human)
Project description: with neural network analysis have been used to address why the alpha- or beta-chain sharing human (More)
Made public: 2014-12-04
Profiling of human lung tissues on 11 normal control, 11 patient and 11 corresponding mouse xenograft tumours
Species: Homo sapiens (Human)
Project description: The total protein expression level of 11 paired human normal, human lung cancer samples and (More)
Made public: 2014-12-04
Stadard peptide mixture plus HeLa
Species: Homo sapiens (Human)
Project description: To test our peak detection and label-free quantitation algorithm (More)
Made public: 2014-12-04
Identification of biomarkers for PKD1 using urinary exosomes
Species: Homo sapiens (Human)
Project description: Autosomal dominant polycystic kidney disease (ADPKD) is a common (More)
Made public: 2014-12-02
Positional proteomics identification of the natural substrates of cytosolic carboxypeptidases
Species: Homo sapiens (Human)
Project description: Cytosolic carboxypeptidases (CCPs) constitute a new subfamily of (More)
Made public: 2014-12-02
Highly sensitive phosphoproteomics by tailoring solid-phase extraction to electrostatic repulsion-hydrophilic interaction chromatography
Species: Homo sapiens (Human)
Project description: The dataset contains the data of key experiments for developing (More)
Made public: 2014-12-02
PBC DIGE
Species: Homo sapiens (Human)
Project description: Analyzing serological differences between AMA positive and negat (More)
Made public: 2014-11-27
The proteome of normal human retina
Species: Homo sapiens (Human)
Project description: proteome of the normal human eye may provide a foundation for new investigations into both the physiology (More)
Made public: 2014-11-27
PBC-DIGE
Species: Homo sapiens (Human)
Project description: DIGE combined with MALDI-TOF-TOF MS/MS was applied to explore t (More)
Made public: 2014-11-27
Hepatic proteome analysis of Atlantic salmon (Salmo salar) after exposure to environmental concentrations of human pharmaceuticals
Species: Salmo sp.
Project description: Pharmaceuticals are pseudo persistent aquatic pollutants with un (More)
Made public: 2014-11-18
Proteomic analysis of urinary exosomes in cystinuria patients
Species: Homo sapiens (Human)
Project description: Cystinuria is a rare renal genetic disease caused by mutations i (More)
Made public: 2014-11-17
The Q Exactive HF, a Benchtop Mass Spectrometer with a Pre-filter, High Performance Quadrupole and an Ultra-High Field Orbitrap Analyzer
Species: Homo sapiens (Human)
Project description: The quadrupole Orbitrap mass spectrometer (Q Exactive) has made (More)
Made public: 2014-11-10
Hendra virus infection of bat (Pteropus alecto) and human cells
Species: Homo sapiens (Human)
Project description: SILAC labeled human kidney cells (293 cells) or bat kidney cells (PakiT03cells)were infected with (More)
Made public: 2014-11-05
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - secreted proteins of dexamethasone-treated inflammatory stimulated cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - cytoplasmic proteins of dexamethasone-treated inflammatory stimulated cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - nuclear proteins of dexamethasone-treated inflammatory stimulated cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - secreted proteins of inflammatory stimulated cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - cytoplasmic proteins of inflammatory stimulated cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - nuclear proteins of inflammatory stimulated cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - secreted proteins of untreated cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - Cytoplasmic Proteins of Untreated Cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - nuclear proteins of untreated cells
Species: Homo sapiens (Human)
Project description: Inflammation is a physiological process involved in many disease (More)
Made public: 2014-11-04
Shotgun ecotoxicoproteomics of Daphnia pulex: biochemical effects of the anticancer drug tamoxifen
Species: Daphnia pulex (Water flea)
Project description: Among pollutants released into the environment by human activities, residues of pharmaceutical (More)
Made public: 2014-10-31
Rapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer
Species: Homo sapiens (Human)
Project description: The faster sequencing speed available on the latest Q Exactive H (More)
Made public: 2014-10-31

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