PDBsum entry 9es6

Chaperone

PDB id: 9es6

Contents

Protein chains

(+ 8 more) 339 a.a.

Ligands

ADP-BEF ×14

Metals

__K ×14

_MG ×14

Waters ×140

PDB id:

9es6

Name:

Chaperone

Title:

Adp:bef3-bound human mitochondrial hsp60 double-ring complex

Structure:

60 kda heat shock protein, mitochondrial. Chain: a, b, c, d, e, f, g, h, i, j, k, l, m, n. Synonym: 60 kda chaperonin,chaperonin 60,cpn60,heat shock protein 60, hsp60,hucha60,mitochondrial matrix protein p1,p60 lymphocyte protein. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hspd1, hsp60. Expressed in: escherichia coli. Expression_system_taxid: 562

Authors:

J.P.Lopez-Alonso,I.Tascon,I.Ubarretxena-Belandia,Y.Shkolnisky

Key ref:

I.Tascon et al. Structural basis for ATP-Triggered assembly of human mitochondrial hsp60-Hsp10 chaperonin. To be published, .

Date:

25-Mar-24 Release date: 09-Apr-25

Protein chains

P10809  (CH60_HUMAN) -  60 kDa heat shock protein, mitochondrial from Homo sapiens

Seq: 573 a.a.

Struc: 339 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.6.4.9 - Transferred entry: 5.6.1.7.
• Reaction: ATP + H₂O = ADP + phosphate

ATP + H(2)O = ADP (Bound ligand (Het Group name = ADP) corresponds exactly) + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site