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PDBsum entry 6y4x
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PDB id:
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Transferase
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Title:
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Crystal structure of p38 in complex with sr72
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Structure:
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Mitogen-activated protein kinase 14. Chain: a. Synonym: mapk 14,crk1,mitogen-activated protein kinase p38 alpha,map kinase p38 alpha. Engineered: yes
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Source:
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Mus musculus. House mouse. Organism_taxid: 10090. Gene: mapk14, crk1, csbp1, csbp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
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Resolution:
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1.60Å
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R-factor:
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0.170
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R-free:
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0.204
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Authors:
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A.Chaikuad,S.Roehm,C.H.Arrowsmith,A.M.Edwards,C.Bountra,S.Knapp, Structural Genomics Consortium (Sgc)
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Date:
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23-Feb-20
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Release date:
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04-Mar-20
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PROCHECK
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Headers
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References
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P47811
(MK14_MOUSE) -
Mitogen-activated protein kinase 14 from Mus musculus
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Seq:
Struc:
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360 a.a.
351 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.2.7.11.24
- mitogen-activated protein kinase.
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Reaction:
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1.
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L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
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2.
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L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
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L-seryl-[protein]
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+
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ATP
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=
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O-phospho-L-seryl-[protein]
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+
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ADP
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+
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H(+)
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L-threonyl-[protein]
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+
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ATP
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=
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O-phospho-L-threonyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
