PDBsum entry 6x9h

Transport protein

PDB id: 6x9h

Contents

Protein chains

409 a.a.

Ligands

NAG ×3

UZG ×3

Metals

_NA

PDB id:

6x9h

Name:

Transport protein

Title:

Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (asic1)

Structure:

Acid-sensing ion channel 1. Chain: a, b, c. Synonym: asic1,amiloride-sensitive cation channel 2,neuronal. Engineered: yes

Source:

Gallus gallus. Chicken. Organism_taxid: 9031. Gene: asic1, accn2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9

Resolution:

3.01Å R-factor: 0.226 R-free: 0.265

Authors:

Y.Liu,J.Ma,R.L.Desjarlais,R.Hagan,J.Rech,D.Lin,C.Liu,R.Miller, J.Schoellerman,J.Luo,M.Letavic,B.Grasberger,M.Maher

Key ref:

R.J.Dawson et al. Structure of the acid-Sensing ion channel 1 in comple the gating modifier psalmotoxin 1.. To be published, 3, . PubMed id: 33564124

Date:

02-Jun-20 Release date: 30-Dec-20

Protein chains

Q1XA76  (ASIC1_CHICK) -  Acid-sensing ion channel 1 from Gallus gallus

Seq: 527 a.a.

Struc: 409 a.a.