PDBsum entry 6w2k

Metal binding protein, oxidoreductase

PDB id: 6w2k

Contents

Protein chains

440 a.a.

Ligands

MPD ×8

MRD

Metals

_CU ×11

Waters ×880

PDB id:

6w2k

Name:

Metal binding protein, oxidoreductase

Title:

Crystal structure of laccase from thermus thermophilus hb27 in reducing conditions (na2,s2,o2, 20 min)

Structure:

Laccase. Chain: a, b. Engineered: yes

Source:

Thermus thermophilus (strain hb27 / atcc baa- 163 / dsm 7039). Organism_taxid: 262724. Strain: hb27 / atcc baa-163 / dsm 7039. Gene: tt_c1370. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

2.00Å R-factor: 0.148 R-free: 0.197

Authors:

R.Miranda-Blancas,E.Rudino-Pinera

Key ref:

R.Miranda-Blancas and e.rudino-pinera Dynamic behavior of alpha-Beta loop at laccase of the thermophilus. To be published, .

Date:

06-Mar-20 Release date: 10-Mar-21

Protein chains

Q72HW2  (Q72HW2_THET2) -  Laccase from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)

Seq: 462 a.a.

Struc: 440 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.1.10.3.2 - laccase.
• Reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O
• Cofactor: Cu cation

Molecule diagrams generated from .mol files obtained from the KEGG ftp site