PDBsum entry 6ubh

Signaling protein

PDB id: 6ubh

Contents

Protein chains

91 a.a.

Ligands

PHE-ASP-PHE-TRP-VAL ×4

Metals

_NA ×3

Waters ×327

PDB id:

6ubh

Name:

Signaling protein

Title:

Structure of the mm7 erbin pdz variant in complex with a high-affinity peptide

Structure:

Erbin. Chain: a, b, c, d. Synonym: densin-180-like protein,erbb2-interacting protein,protein lap2. Engineered: yes. Mutation: yes. Peptide. Chain: e, f, g, h. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: erbin, erbb2ip, kiaa1225, lap2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630

Resolution:

1.80Å R-factor: 0.210 R-free: 0.225

Authors:

A.U.Singer,J.Teyra,M.Mclaughlin,A.Ernst,F.Sicheri,S.S.Sidhu

Key ref:

J.Teyra et al. Directed evolution of pdz fold specificity for a sing peptide position. To be published, . PubMed id: 34171344

Date:

11-Sep-19 Release date: 29-Jul-20

Protein chains

Q96RT1  (ERBIN_HUMAN) -  Erbin from Homo sapiens

Seq: 1412 a.a.

Struc: 91 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)