PDBsum entry 6pv8

Membrane protein

PDB id: 6pv8

Contents

Protein chains

387 a.a.

388 a.a.

117 a.a.

105 a.a.

Ligands

NAG-NAG ×2

NAG-NAG-BMA-MAN-MAN ×5

NAG-NAG-BMA ×3

P1M ×2

Y01 ×10

NAG ×6

Metals

_NA

Waters ×8

PDB id:

6pv8

Name:

Membrane protein

Title:

Human alpha3beta4 nicotinic acetylcholine receptor in complex with at- 1001

Structure:

Fusion protein of neuronal acetylcholine receptor subunit alpha-3 and soluble cytochrome b562. Chain: a, d. Engineered: yes. Fusion protein of neuronal acetylcholine receptor subunit beta-4 and soluble cytochrome b562. Chain: b, c, e. Engineered: yes. Igg2b fab heavy chain.

Source:

Homo sapiens, escherichia coli o11. Human. Organism_taxid: 9606, 1095705. Gene: chrna3, nachra3, cwj32_12820. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_variant: gnti-. Expression_system_cell_line: hek293. Expression_system_atcc_number: crl-3022.

Authors:

A.Gharpure,J.Teng,Y.Zhuang,C.M.Noviello,R.M.Walsh,R.Cabuco, R.J.Howard,N.T.Zaveri,E.Lindahl,R.E.Hibbs

Date:

19-Jul-19 Release date: 11-Sep-19

Protein chains

P32297  (ACHA3_HUMAN) -  Neuronal acetylcholine receptor subunit alpha-3 from Homo sapiens

Seq: 505 a.a.

Struc: 387 a.a.

Protein chains

P30926  (ACHB4_HUMAN) -  Neuronal acetylcholine receptor subunit beta-4 from Homo sapiens

Seq: 498 a.a.

Struc: 388 a.a.

Protein chains

No UniProt id for this chain

Struc: 117 a.a.

Protein chains

No UniProt id for this chain

Struc: 105 a.a.