PDBsum entry 6nq0

Transport protein

PDB id: 6nq0

Contents

Protein chains

621 a.a.

Ligands

EUJ ×2

PDB id:

6nq0

Name:

Transport protein

Title:

Cryo-em structure of human tpc2 channel in the ligand-bound open state

Structure:

Two pore calcium channel protein 2. Chain: a, b. Synonym: voltage-dependent calcium channel protein tpc2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: tpcn2, tpc2. Expressed in: homo sapiens. Expression_system_taxid: 9606

Authors:

J.She,W.Zeng,J.Guo,Q.Chen,X.Bai,Y.Jiang

Key ref:

J.She et al. (2019). Structural mechanisms of phospholipid activation of t human tpc2 channel.. Elife, 8, . PubMed id: 30860481

Date:

18-Jan-19 Release date: 27-Mar-19

Protein chains

Q8NHX9  (TPC2_HUMAN) -  Two pore channel protein 2 from Homo sapiens

Seq: 752 a.a.

Struc: 621 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)