PDBsum entry 6npm

Viral protein/inhibitor

PDB id: 6npm

Contents

Protein chains

141 a.a.

134 a.a.

Ligands

KVD

Waters ×447

PDB id:

6npm

Name:

Viral protein/inhibitor

Title:

Crystal structure of epstein-barr virus nuclear antigen-1, ebna1, bound to fragments

Structure:

Epstein-barr nuclear antigen 1. Chain: a, b. Synonym: ebv nuclear antigen 1. Engineered: yes

Source:

Epstein-barr virus (strain b95-8). Hhv-4. Organism_taxid: 10377. Strain: b95-8. Gene: ebna1, bkrf1. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.60Å R-factor: 0.145 R-free: 0.170

Authors:

T.E.Messick

Key ref:

T.E.Messick et al. (2019). Structure-Based design of small-Molecule inhibitors o DNA binding blocks epstein-Barr virus latent infectio tumor growth.. Sci transl med, 11, . PubMed id: 30842315

Date:

17-Jan-19 Release date: 20-Mar-19

Protein chain

P03211  (EBNA1_EBVB9) -  Epstein-Barr nuclear antigen 1 from Epstein-Barr virus (strain B95-8)

Seq: 641 a.a.

Struc: 141 a.a.*

Protein chain

P03211  (EBNA1_EBVB9) -  Epstein-Barr nuclear antigen 1 from Epstein-Barr virus (strain B95-8)

Seq: 641 a.a.

Struc: 134 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)