PDBsum entry 6ndh

Cell adhesion/toxin

PDB id: 6ndh

Contents

Protein chains

(+ 0 more) 131 a.a.

(+ 0 more) 122 a.a.

(+ 0 more) 191 a.a.

Ligands

SO4 ×15

NH4

Metals

_CL ×9

_NA ×6

_ZN ×6

Waters ×7

PDB id:

6ndh

Name:

Cell adhesion/toxin

Title:

Rhodocetin in complex with the integrin alpha2-a domain and zinc

Structure:

Snaclec rhodocetin subunit gamma. Chain: a, d, g, j, m, p. Snaclec rhodocetin subunit delta. Chain: b, e, h, k, n, q. Integrin alpha-2. Chain: c, f, i, l, o, r. Synonym: cd49 antigen-like family member b,collagen receptor,platelet membrane glycoprotein ia,gpia,vla-2 subunit alpha. Engineered: yes

Source:

Calloselasma rhodostoma. Malayan pit viper. Organism_taxid: 8717. Homo sapiens. Human. Organism_taxid: 9606. Gene: itga2, cd49b. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.90Å R-factor: 0.231 R-free: 0.285

Authors:

J.Stetefeld,M.D.Mcdougall,P.C.Loewen

Key ref:

J.Stetefeld et al. Rhodocetin in complex with the integrin alpha2-A doma zinc bound. To be published, .

Date:

13-Dec-18 Release date: 23-Jan-19

Protein chains

D2YW39  (SLEC_CALRH) -  Snaclec rhodocetin subunit gamma (Fragment) from Calloselasma rhodostoma

Seq: 135 a.a.

Struc: 131 a.a.

Protein chains

D2YW40  (SLED_CALRH) -  Snaclec rhodocetin subunit delta from Calloselasma rhodostoma

Seq: 124 a.a.

Struc: 122 a.a.

Protein chains

P17301  (ITA2_HUMAN) -  Integrin alpha-2 from Homo sapiens

Seq: 1181 a.a.

Struc: 191 a.a.