PDBsum entry 6mpp

Immune system

PDB id: 6mpp

Contents

Protein chains

274 a.a.

100 a.a.

Ligands

ILE-LEU-ASP-THR-ALA-GLY-LYS-GLU-GLU-TYR

PDB id:

6mpp

Name:

Immune system

Title:

Hla-a 01:01 Complex with nras q61k peptide by nmr

Structure:

Hla class i histocompatibility antigen, a-1 alpha chain. Chain: a. Fragment: residues 25-303. Synonym: mhc class i antigen a 1. Engineered: yes. Nras q61k peptide. Chain: b. Engineered: yes. Beta-2-microglobulin.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-a, hlaa. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: b2m, cdabp0092, hdcma22p. Expression_system_taxid: 562

NMR struc:

10 models

Authors:

D.Flores-Solis,A.C.Mcshan,N.G.Sgourakis

Key ref:

D.Flores-Solis et al. Mhc-I complex determined by nmr. To be published, .

Date:

08-Oct-18 Release date: 16-Oct-19

Protein chain

P04439  (1A03_HUMAN) -  HLA class I histocompatibility antigen, A alpha chain from Homo sapiens

Seq: 365 a.a.

Struc: 274 a.a.*

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 16 residue positions (black crosses)