PDBsum entry 6frd

Hydrolase

PDB id: 6frd

Contents

Protein chains

332 a.a.

Ligands

GAI ×7

FMT ×2

E3Q

Metals

_ZN ×2

_MG ×2

Waters ×189

PDB id:

6frd

Name:

Hydrolase

Title:

Crystal structure of t. Brucei pde-b1 catalytic domain with inhibitor npd-637

Structure:

Phosphodiesterase. Chain: a, b. Engineered: yes. Other_details: residues 565-918

Source:

Trypanosoma brucei. Organism_taxid: 5691. Gene: pdeb1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

2.20Å R-factor: 0.171 R-free: 0.209

Authors:

A.K.Singh,D.G.Brown

Key ref:

A.K.Singh and d.g.brown Crystal structure of t. Brucei pde-B1 catalytic domai inhibitor npd-637. To be published, .

Date:

15-Feb-18 Release date: 13-Mar-19

Protein chains

Q8WQX9  (Q8WQX9_9TRYP) -  Phosphodiesterase from Trypanosoma brucei

Seq: 930 a.a.

Struc: 332 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.4.- - ?????