PDBsum entry 6e1h

Membrane protein

PDB id: 6e1h

Contents

Protein chains

978 a.a.

164 a.a.

Ligands

PLM

Metals

_ZN

_CA ×2

PDB id:

6e1h

Name:

Membrane protein

Title:

Structure of 2:1 human ptch1-shh-n complex

Structure:

Protein patched homolog 1. Chain: a, b. Synonym: ptc1. Engineered: yes. Sonic hedgehog protein. Chain: c. Synonym: shh,hhg-1,shh unprocessed n-terminal signaling and c- terminal autoprocessing domains,shhnc. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ptch1, ptch. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: shh. Expression_system_taxid: 9606

Authors:

X.Qi,X.Li

Key ref:

x.qi et al. (2018). Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex. Science, 0, . PubMed id: 30139912

Date:

09-Jul-18 Release date: 29-Aug-18

Protein chains

Q13635  (PTC1_HUMAN) -  Protein patched homolog 1 from Homo sapiens

Seq: 1447 a.a.

Struc: 978 a.a.

Protein chain

Q15465  (SHH_HUMAN) -  Sonic hedgehog protein from Homo sapiens

Seq: 462 a.a.

Struc: 164 a.a.

Enzyme reactions

• Enzyme class: Chain C: E.C.3.1.-.-

Science 0: (2018)

PubMed id: 30139912

Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex.

x.qi, p.schmiege, e.coutavas, x.li.

ABSTRACT

No abstract given.