PDBsum entry 6b4z

Transferase

PDB id: 6b4z

Contents

Protein chain

256 a.a.

Ligands

A3P

TRS

Waters ×430

PDB id:

6b4z

Name:

Transferase

Title:

Schistosoma mansoni (blood fluke) sulfotransferase, t157s mutant

Structure:

Sulfotransferase oxamniquine resistance protein. Chain: a. Synonym: sulfotransferase. Engineered: yes. Mutation: yes

Source:

Schistosoma mansoni. Blood fluke. Organism_taxid: 6183. Gene: sult-or, smp_089320. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.

Resolution:

1.74Å R-factor: 0.176 R-free: 0.208

Authors:

A.B.Taylor

Key ref:

P.T.Loverde Why does oxamniquine kill schistosoma mansoni and not haematobium and s. Japonicum?. To be published, .

Date:

27-Sep-17 Release date: 10-Oct-18

Protein chain

G4VLE5  (G4VLE5_SCHMA) -  Sulfotransferase oxamniquine resistance protein from Schistosoma mansoni

Seq: 257 a.a.

Struc: 256 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.8.2.- - ?????