PDBsum entry 5umd

RIBOSOME

PDB id

5umd

Contents

			Protein chains

					×37 chains

			Ligands

					YMZ ×2

			Metals

					_ZN ×5


					_MG ×164

PDB id:

5umd

Links

Name:

RIBOSOME

Title:

Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine

Structure:

60S ribosomal protein L2, 60S ribosomal protein L3, 60S ribosomal protein L4, 60S ribosomal protein L11a, putative, 60S ribosomal protein L6, putative, 60S ribosomal protein L6-2, putative, 60S ribosomal protein L7-3, putative, 60S ribosomal protein L13, putative, 60S ribosomal protein L13, 60S ribosomal protein L23, putative, 60S ribosomal protein L14, putative, 60S ribosomal protein L27a, putative, Ribosomal protein L15, 60S ribosomal protein L10, putative, 60S ribosomal protein L5, putative, 60S ribosomal protein L18-2, putative, 60S ribosomal protein L19, 60S ribosomal protein L18a, 60S ribosomal protein L21, 60S ribosomal protein L17, putative, 60S ribosomal protein L22, putative, 60S ribosomal protein L23, 60S ribosomal protein L26, putative, 60S ribosomal protein L24, putative, 60S ribosomal protein L27, 60S ribosomal protein L28, 60S ribosomal protein L35, putative, 60S ribosomal protein L29, putative, 60S ribosomal protein L7, putative, 60S ribosomal protein L30e, putative, 60S ribosomal protein L

Authors:

Wong, W., Bai, X.-C., Brown, A., Scheres, S., Baum, J.

Key ref:

(2017). Mefloquine targets the plasmodium falciparum 80s ribosome to inhibit protein synthesis.. Nat microbiol, 2, 17031-17031. PubMed id: 28288098

Note. PDBsum analyses are not available for this structure because of its large size. To get more detailed information on it, please go to its PDBe page.