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PDBsum entry 5qos
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PDB id:
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Hydrolase
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Title:
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Pandda analysis group deposition -- crystal structure of dcp2 (nudt20) in complex with z1187701032
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Structure:
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Dcp2 (nudt20). Chain: a. Fragment: unp residues 95-260. Synonym: nucleoside diphosphate-linked moiety x motif 20, nudix motif 20, mRNA-decapping enzyme 2, hdpc, m7gpppn-mRNA hydrolase. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: dcp2, nudt20. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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1.70Å
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R-factor:
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0.197
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R-free:
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0.252
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Authors:
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E.R.Nelson,S.Velupillai,R.Talon,P.M.Collins,T.Krojer,D.Wang, J.Brandao-Neto,A.Douangamath,N.Burgess-Brown,C.H.Arrowsmith, C.Bountra,K.Huber,F.Von Delft
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Key ref:
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E.R.Nelson
et al.
Pandda analysis group deposition.
To be published,
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Date:
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22-Feb-19
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Release date:
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08-May-19
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PROCHECK
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Headers
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References
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Q8IU60
(DCP2_HUMAN) -
m7GpppN-mRNA hydrolase from Homo sapiens
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Seq:
Struc:
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420 a.a.
149 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.3.6.1.62
- 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase.
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Reaction:
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a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = N(7)-methyl-GDP + a 5'-end phospho-ribonucleoside in mRNA + 2 H+
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Links
