PDBsum entry 5ipc

Hydrolase

PDB id: 5ipc

Contents

Protein chains

115 a.a.

Ligands

6CE

EDO ×3

Metals

_CL

Waters ×228

PDB id:

5ipc

Name:

Hydrolase

Title:

Human histidine triad nucleotide binding protein 1 (hhint1) h112n mutant nucleoside thiophosphoramidate substrate complex

Structure:

Histidine triad nucleotide-binding protein 1. Chain: a, b. Synonym: adenosine 5'-monophosphoramidase. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hint1, hint. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.30Å R-factor: 0.153 R-free: 0.170

Authors:

K.M.Maize,B.C.Finzel

Key ref:

K.M.Maize Structural biology for drug design: applications in t systems. Retrieved from the university of minnesota d conservancy, Http://hdl.Handle.Net/11299/182796. Thesis, University of, . PubMed id: 28691797

Date:

09-Mar-16 Release date: 15-Mar-17

Protein chains

P49773  (HINT1_HUMAN) -  Adenosine 5'-monophosphoramidase HINT1 from Homo sapiens

Seq: 126 a.a.

Struc: 115 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class 2: E.C.3.4.22.- - ?????
• Enzyme class 3: E.C.3.9.1.- - ?????

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.