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PDBsum entry 5eqc
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PDB id:
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Transferase
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Title:
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Structure of the ornithine aminotransferase from toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of plp at the protein active site
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Structure:
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Ornithine aminotransferase, mitochondrial. Chain: a, b. Engineered: yes
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Source:
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Toxoplasma gondii. Organism_taxid: 5811. Strain: me49. Gene: tgme49_269110. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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2.20Å
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R-factor:
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0.146
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R-free:
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0.181
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Authors:
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E.V.Filippova,G.Minasov,K.Flores,H.V.Le,R.B.Silverman,R.L.Mcleod, W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid)
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Key ref:
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E.V.Filippova
et al.
Structure of the ornithine aminotransferase from toxo gondii crystallized in presence of oxidized glutathio reveals partial occupancy of plp at the protein activ.
To be published,
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Date:
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12-Nov-15
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Release date:
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24-Feb-16
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PROCHECK
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Headers
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References
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S8EY38
(S8EY38_TOXGM) -
Ornithine aminotransferase from Toxoplasma gondii (strain ATCC 50611 / Me49)
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Seq:
Struc:
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441 a.a.
426 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.6.1.13
- ornithine aminotransferase.
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Reaction:
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a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid
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2-oxocarboxylate
Bound ligand (Het Group name = )
matches with 45.45% similarity
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+
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L-ornithine
Bound ligand (Het Group name = )
matches with 50.00% similarity
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=
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L-glutamate 5-semialdehyde
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+
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L-alpha-amino acid
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Cofactor:
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Pyridoxal 5'-phosphate
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Pyridoxal 5'-phosphate
Bound ligand (Het Group name =
PLP)
corresponds exactly
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
