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PDBsum entry 4zuc
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Transcription
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PDB id
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4zuc
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| Superseded by: |
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PDB id:
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| Name: |
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Transcription
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Title:
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Crystal structure of the er-alpha ligand-binding domain (y537s) in complex with an n-methyl substituted obhs-n derivative
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Structure:
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Estrogen receptor. Chain: a, b. Fragment: ligand-binding domain, unp residues 305-549. Synonym: er,er-alpha,estradiol receptor,nuclear receptor subfamily 3 group a member 1. Engineered: yes. Mutation: yes. Nuclear receptor-interacting peptide. Chain: c, d.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: esr1, esr, nr3a1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
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Resolution:
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1.82Å
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R-factor:
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0.183
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R-free:
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0.206
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Authors:
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J.C.Nwachukwu,S.Srinivasan,Y.Zheng,S.Wang,J.Min,C.Dong,Z.Liao, V.Cavett,J.Nowak,R.Houtman,K.E.Carlson,J.S.Josan,O.Elemento, J.A.Katzenellenbogen,H.B.Zhou,K.W.Nettles
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Key ref:
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J.C.Nwachukwu
et al.
Predicting proliferative effects of estrogen receptor ligands.
To be published,
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Date:
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15-May-15
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Release date:
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01-Jun-16
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PROCHECK
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Headers
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References
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P03372
(ESR1_HUMAN) -
Estrogen receptor from Homo sapiens
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Seq:
Struc:
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595 a.a.
231 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Links
