PDBsum entry 4zlr

Translation

PDB id: 4zlr

Contents

Protein chains

278 a.a.

DNA/RNA

Ligands

PE4

SO4 ×9

PG4

1PE

Waters ×338

PDB id:

4zlr

Name:

Translation

Title:

Structure of the brat-nhl domain bound to consensus RNA motif

Structure:

Brain tumor protein. Chain: a, b. Fragment: unp residues 756-1037. Engineered: yes. RNA (5'-r( Up Up Gp Up Up Gp Up Up Up Up Up Up Up U)-3'). Chain: c. Engineered: yes

Source:

Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: brat, cg10719. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630

Resolution:

2.30Å R-factor: 0.189 R-free: 0.219

Authors:

L.Jakob,N.Treiber,T.Treiber,M.Stotz,I.Loedige,G.Meister

Key ref:

I.Loedige et al. (2015). The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation. Cell Rep, 13, 1206-1220. PubMed id: 26527002 DOI: 10.1016/j.celrep.2015.09.068

Date:

01-May-15 Release date: 11-Nov-15

Protein chains

Q8MQJ9  (BRAT_DROME) -  Protein brain tumor from Drosophila melanogaster

Seq: 1037 a.a.

Struc: 278 a.a.

DNA/RNA chain

U-U-G-U-U-G-U-U-U-U-U-U-U-U 14 bases

DOI no: 10.1016/j.celrep.2015.09.068

Cell Rep 13:1206-1220 (2015)

PubMed id: 26527002

The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation.

I.Loedige, L.Jakob, T.Treiber, D.Ray, M.Stotz, N.Treiber, J.Hennig, K.B.Cook, Q.Morris, T.R.Hughes, J.C.Engelmann, M.P.Krahn, G.Meister.

ABSTRACT

No abstract given.