PDBsum entry 4x86

Protein binding

PDB id: 4x86

Contents

Protein chains

51 a.a.

56 a.a.

Ligands

CPS

SO4 ×2

Waters ×21

PDB id:

4x86

Name:

Protein binding

Title:

Crystal structure of bag6-ubl4a complex

Structure:

Ubiquitin-like protein 4a. Chain: a. Fragment: unp residues 95-147. Synonym: ubiquitin-like protein gdx. Engineered: yes. Large proline-rich protein bag6. Chain: b. Fragment: unp residues 1048-1123. Synonym: bag family molecular chaperone regulator 6,bcl2-associated

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ubl4a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: bag6.

Resolution:

1.85Å R-factor: 0.208 R-free: 0.237

Authors:

N.Kuwabara,R.Kato

Key ref:

N.Kuwabara et al. (2015). Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis. J Biol Chem, 290, 9387-9398. PubMed id: 25713138 DOI: 10.1074/jbc.M114.631804

Date:

10-Dec-14 Release date: 25-Feb-15

Protein chain

P11441  (UBL4A_HUMAN) -  Ubiquitin-like protein 4A from Homo sapiens

Seq: 157 a.a.

Struc: 51 a.a.*

Protein chain

P46379  (BAG6_HUMAN) -  Large proline-rich protein BAG6 from Homo sapiens

Seq: 1132 a.a.

Struc: 56 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

DOI no: 10.1074/jbc.M114.631804

J Biol Chem 290:9387-9398 (2015)

PubMed id: 25713138

Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis.

N.Kuwabara, R.Minami, N.Yokota, H.Matsumoto, T.Senda, H.Kawahara, R.Kato.

ABSTRACT

No abstract given.