PDBsum entry 4x7f

Viral protein

PDB id: 4x7f

Contents

Protein chains

307 a.a.

114 a.a.

Ligands

EDO ×23

PO4

IMD ×2

Metals

_NA

Waters ×464

PDB id:

4x7f

Name:

Viral protein

Title:

Crystal structure of norovirus gii.10 p domain in complex with nano-25

Structure:

Capsid protein. Chain: a, b. Fragment: vhh, unp residues 224-538. Engineered: yes. Nano-25 nanobody. Chain: c, d. Engineered: yes

Source:

Norwalk virus. Organism_taxid: 11983. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Vicugna pacos. Organism_taxid: 30538. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: wk6.

Resolution:

1.70Å R-factor: 0.161 R-free: 0.187

Authors:

A.D.Koromyslova,G.S.Hansman

Key ref:

A.D.Koromyslova and G.S.Hansman (2015). Nanobody binding to a conserved epitope promotes norovirus particle disassembly. J Virol, 89, 2718-2730. PubMed id: 25520510 DOI: 10.1128/JVI.03176-14

Date:

09-Dec-14 Release date: 31-Dec-14

Protein chains

Q5F4T5  (Q5F4T5_9CALI) -  Capsid protein from Norwalk virus

Seq: 548 a.a.

Struc: 307 a.a.

Protein chains

No UniProt id for this chain

Struc: 114 a.a.

DOI no: 10.1128/JVI.03176-14

J Virol 89:2718-2730 (2015)

PubMed id: 25520510

Nanobody binding to a conserved epitope promotes norovirus particle disassembly.

A.D.Koromyslova, G.S.Hansman.

ABSTRACT

No abstract given.