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PDBsum entry 4o3c
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Membrane protein/agonist
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PDB id
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4o3c
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PDB id:
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| Name: |
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Membrane protein/agonist
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Title:
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Crystal structure of the glua2 ligand-binding domain in complex with l-aspartate at 1.50 a resolution
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Structure:
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Glutamate receptor 2. Chain: a. Fragment: ligand binding domain (unp residues 413-527 and unp residues 653-796). Synonym: glur-2,ampa-selective glutamate receptor 2,glur-b,glur-k2, glutamate receptor ionotropic,ampa 2. Engineered: yes
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Source:
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Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: gria2, glur2. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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1.50Å
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R-factor:
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0.129
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R-free:
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0.158
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Authors:
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C.Krintel,K.Frydenvang,A.M.Kaern,M.Gajhede,J.S.Kastrup
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Key ref:
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C.Krintel
et al.
(2014).
L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain.
Febs J,
281,
2422-2430.
PubMed id:
DOI:
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Date:
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18-Dec-13
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Release date:
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16-Apr-14
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PROCHECK
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Headers
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References
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P19491
(GRIA2_RAT) -
Glutamate receptor 2 from Rattus norvegicus
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Seq:
Struc:
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883 a.a.
262 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 4 residue positions (black
crosses)
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DOI no:
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Febs J
281:2422-2430
(2014)
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PubMed id:
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L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain.
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C.Krintel,
K.Frydenvang,
A.Ceravalls de Rabassa,
A.M.Kaern,
M.Gajhede,
D.S.Pickering,
J.S.Kastrup.
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ABSTRACT
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Links
