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PDBsum entry 4m89

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protein ligands Protein-protein interface(s) links
Oxidoreductase/antibiotic PDB id
4m89
Jmol
Contents
Protein chains
257 a.a.
Ligands
NAD ×2
TCL ×2
Waters ×314
PDB id:
4m89
Name: Oxidoreductase/antibiotic
Title: Crystal structure of enoyl-acyl carrier protein reductase (f neisseria meningitidis in complex with NAD+ and triclosan
Structure: Enoyl-[acyl-carrier-protein] reductase [nadh]. Chain: a, b. Engineered: yes
Source: Neisseria meningitidis. Organism_taxid: 272831. Strain: fam18. Gene: fabi, nmc1834. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.90Å     R-factor:   0.168     R-free:   0.186
Authors: J.D.Nanson,J.K.Forwood
Date:
13-Aug-13     Release date:   02-Oct-13    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
A1KVU8  (A1KVU8_NEIMF) -  Enoyl-[acyl-carrier-protein] reductase [NADH]
Seq:
Struc:
261 a.a.
257 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.3.1.9  - Enoyl-[acyl-carrier-protein] reductase (NADH).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: An acyl-[acyl-carrier protein] + NAD+ = a trans-2,3-dehydroacyl-[acyl- carrier protein] + NADH
acyl-[acyl-carrier protein]
+ NAD(+)
= trans-2,3-dehydroacyl-[acyl- carrier protein]
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   3 terms 
  Biochemical function     nucleotide binding     3 terms