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PDBsum entry 4lyn

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protein ligands links
Transferase/transferase inhibitor PDB id
4lyn
Jmol
Contents
Protein chain
287 a.a.
Ligands
1YG
Waters ×90
PDB id:
4lyn
Name: Transferase/transferase inhibitor
Title: Crystal structure of cyclin-dependent kinase 2 (cdk2-wt) com (2s)-n-(5-(((5-tert-butyl-1,3-oxazol-2-yl)methyl)sulfanyl)- thiazol-2-yl)-2-phenylpropanamide
Structure: Cyclin-dependent kinase 2. Chain: a. Synonym: cell division protein kinase 2, p33 protein kinase engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdk2, cdkn2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.00Å     R-factor:   0.187     R-free:   0.238
Authors: J.S.Sack
Date:
31-Jul-13     Release date:   02-Oct-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P24941  (CDK2_HUMAN) -  Cyclin-dependent kinase 2
Seq:
Struc:
298 a.a.
287 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.22  - Cyclin-dependent kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cyclin-dependent protein kinase holoenzyme complex   15 terms 
  Biological process     regulation of gene silencing   27 terms 
  Biochemical function     nucleotide binding     12 terms