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PDBsum entry 4k7m

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protein ligands metals links
Hydrolase PDB id
4k7m
Jmol
Contents
Protein chain
118 a.a.
Ligands
SO4 ×2
Metals
_HG ×2
Waters ×102
PDB id:
4k7m
Name: Hydrolase
Title: Crystal structure of rnase s variant (k7c/q11c) with bound m ions
Structure: Ribonuclease pancreatic. Chain: a. Fragment: unp residues 27-150. Synonym: rnase 1, rnase a. Mutation: yes
Source: Bos taurus. Cow. Organism_taxid: 9913
Resolution:
1.80Å     R-factor:   0.167     R-free:   0.205
Authors: M.Genz,N.Straeter
Key ref: M.Genz et al. (2013). Crystal structure of apo- And metalated thiolate cont rnase s as structural basis for the design of artific metalloenzymes by peptide- Protein complementation. Z.Anorg.Allg.Chem., 639, 2395. DOI: 10.1002/ZAAC.201300410
Date:
17-Apr-13     Release date:   27-Nov-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P61823  (RNAS1_BOVIN) -  Ribonuclease pancreatic
Seq:
Struc:
150 a.a.
118 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.1.27.5  - Pancreatic ribonuclease.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   1 term 
  Biological process     metabolic process   3 terms 
  Biochemical function     nucleic acid binding     7 terms