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PDBsum entry 4iiu

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
4iiu
Jmol
Contents
Protein chains
243 a.a.
Ligands
NAP ×4
Waters ×495
PDB id:
4iiu
Name: Oxidoreductase
Title: Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from escherichia coli strain cft073 compl NADP+ at 2.1 a resolution
Structure: 3-oxoacyl-[acyl-carrier protein] reductase. Chain: a, b, c, d. Synonym: beta-ketoacyl-acyl carrier protein reductase, fabg engineered: yes. Mutation: yes
Source: Escherichia coli. Organism_taxid: 199310. Strain: cft073 / atcc 700928 / upec. Gene: c1187, nt04ec1225. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
2.10Å     R-factor:   0.169     R-free:   0.193
Authors: J.Hou,T.Osinski,H.Zheng,I.Shumilin,I.Shabalin,S.Shatsman, W.F.Anderson,W.Minor,Center For Structural Genomics Of Infe Diseases (Csgid)
Key ref: J.Hou et al. Crystal structure of a putative 3-Oxoacyl-[Acyl-Carri protein]reductase from escherichia coli strain cft073 complexed with NADP+ at 2.1 a resolution. To be published, .
Date:
20-Dec-12     Release date:   09-Jan-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q8FJ14  (Q8FJ14_ECOL6) -  3-oxoacyl-[acyl-carrier protein] reductase
Seq:
Struc:
243 a.a.
243 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.100  - 3-oxoacyl-[acyl-carrier-protein] reductase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl- carrier-protein] + NADPH
(3R)-3-hydroxyacyl-[acyl-carrier-protein]
+ NADP(+)
= 3-oxoacyl-[acyl- carrier-protein]
+ NADPH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   2 terms 
  Biochemical function     nucleotide binding     3 terms