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PDBsum entry 4i1i

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
4i1i
Jmol
Contents
Protein chains
320 a.a.
Ligands
NAD
PO4 ×3
EDO ×5
Waters ×623
PDB id:
4i1i
Name: Oxidoreductase
Title: Crystal structure of a putative cytosolic malate dehydrogena leishmania major friedlin in complex with NAD
Structure: Malate dehydrogenase. Chain: a, b. Engineered: yes
Source: Leishmania major. Organism_taxid: 347515. Strain: friedlin. Gene: cmdh, lmjf_28_2860. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.50Å     R-factor:   0.146     R-free:   0.166
Authors: Seattle Structural Genomics Center For Infectious Disease
Key ref: Ssgcid et al. Crystal structure of a putative cytosolic malate dehydrogenase from leishmania major friedlin in compl NAD. To be published, .
Date:
21-Nov-12     Release date:   19-Dec-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q4Q7X6  (Q4Q7X6_LEIMA) -  Malate dehydrogenase
Seq:
Struc:
324 a.a.
320 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.37  - Malate dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Citric acid cycle
      Reaction: (S)-malate + NAD+ = oxaloacetate + NADH
(S)-malate
+ NAD(+)
= oxaloacetate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
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  Cellular component     cytosol   1 term 
  Biological process     oxidation-reduction process   5 terms 
  Biochemical function     catalytic activity     6 terms