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PDBsum entry 4h81

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protein ligands metals links
Transferase/transferase inhibitor PDB id
4h81
Jmol
Contents
Protein chain
303 a.a.
Ligands
ADP
WJ2
Metals
_MG
__K
Waters ×97
PDB id:
4h81
Name: Transferase/transferase inhibitor
Title: Crystal structure of branched-chain alpha-ketoacid dehydroge kinase/(r)-2-chloro-3-phenylpropanoic acid complex with adp
Structure: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide mitochondrial. Chain: a. Synonym: branched-chain alpha-ketoacid dehydrogenase kinase kinase, bckdhkin. Engineered: yes
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: bckdk. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.05Å     R-factor:   0.208     R-free:   0.235
Authors: S.C.Tso,J.L.Chuang,W.J.Gui,R.M.Wynn,J.Li,D.T.Chuang
Date:
21-Sep-12     Release date:   05-Jun-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q00972  (BCKD_RAT) -  [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
Seq:
Struc:
412 a.a.
303 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.4  - [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] = ADP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] phosphate
ATP
+ [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)]
= ADP
+ [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     mitochondrion   3 terms 
  Biological process     phosphorylation   3 terms 
  Biochemical function     nucleotide binding     8 terms