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PDBsum entry 4gl1

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protein metals links
Lyase PDB id
4gl1
Jmol
Contents
Protein chain
258 a.a.
Metals
_ZN
Waters ×206
PDB id:
4gl1
Name: Lyase
Title: Structure of h64a/n62l/n67l human carbonic anhydrase ii trip
Structure: Carbonic anhydrase 2. Chain: x. Synonym: carbonate dehydratase ii, carbonic anhydrasE C, ca carbonic anhydrase ii, ca-ii. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.50Å     R-factor:   0.171     R-free:   0.194
Authors: D.M.West
Key ref: D.M.West et al. Hydrophobicity and low pka impact catalytic efficienc human carbonic anhydrases. To be published, .
Date:
13-Aug-12     Release date:   04-Sep-13    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2
Seq:
Struc:
260 a.a.
258 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.1  - Carbonate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: H2CO3 = CO2 + H2O
H(2)CO(3)
= CO(2)
+ H(2)O
      Cofactor: Zn(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular space   11 terms 
  Biological process     angiotensin-mediated signaling pathway   22 terms 
  Biochemical function     protein binding     5 terms