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PDBsum entry 4fv6

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protein ligands links
Transferase PDB id
4fv6
Jmol
Contents
Protein chain
332 a.a.
Ligands
E57
SO4 ×3
EDO
Waters ×77
PDB id:
4fv6
Name: Transferase
Title: Crystal structure of the erk2 complexed with e57
Structure: Mitogen-activated protein kinase 1. Chain: a. Synonym: map kinase 1, mapk 1, ert1, extracellular signal-r kinase 2, erk-2, map kinase isoform p42, p42-mapk, mitogen- protein kinase 2, map kinase 2, mapk 2. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: human. Gene: erk2, mapk1, prkm1, prkm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.50Å     R-factor:   0.222     R-free:   0.249
Authors: Y.N.Kang,J.A.Stuckey,Vertex-Crystallographers
Key ref: Y.N.Kang et al. Crystal structure of the erk2 complexed with e57. To be published, .
Date:
29-Jun-12     Release date:   29-Aug-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P28482  (MK01_HUMAN) -  Mitogen-activated protein kinase 1
Seq:
Struc:
360 a.a.
332 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.24  - Mitogen-activated protein kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     protein complex   21 terms 
  Biological process     viral reproduction   73 terms 
  Biochemical function     nucleotide binding     15 terms