spacer
spacer

PDBsum entry 4fuy

Go to PDB code: 
protein ligands links
Transferase PDB id
4fuy
Jmol
Contents
Protein chain
332 a.a.
Ligands
EK2
SO4 ×2
EDO
Waters ×202
PDB id:
4fuy
Name: Transferase
Title: Crystal structure of the erk2 complexed with ek2
Structure: Mitogen-activated protein kinase 1. Chain: a. Synonym: map kinase 1, mapk 1, ert1, extracellular signal-r kinase 2, erk-2, map kinase isoform p42, p42-mapk, mitogen- protein kinase 2, map kinase 2, mapk 2. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: human. Gene: erk2, mapk1, prkm1, prkm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.00Å     R-factor:   0.190     R-free:   0.217
Authors: Y.N.Kang,J.A.Stuckey,X.Xie
Key ref: Y.N.Kang et al. Crystal structure of the erk2 complexed with ek2. To be published, .
Date:
28-Jun-12     Release date:   22-Aug-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P28482  (MK01_HUMAN) -  Mitogen-activated protein kinase 1
Seq:
Struc:
360 a.a.
332 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.24  - Mitogen-activated protein kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     protein complex   21 terms 
  Biological process     viral reproduction   75 terms 
  Biochemical function     nucleotide binding     16 terms