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PDBsum entry 4fs0

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protein ligands links
Cell adhesion PDB id
4fs0
Jmol
Contents
Protein chain
218 a.a.
Ligands
NAG-NAG-FUC
SO4
Waters ×12
PDB id:
4fs0
Name: Cell adhesion
Title: Crystal structure of mutant f136d of mouse nectin-2 extracel fragment d1-d2
Structure: Poliovirus receptor-related protein 2. Chain: a. Fragment: extracellular domain (d1-d2, unp residues 32-250) synonym: nectin-2, herpes virus entry mediator b, herpesvir mediator b, hveb, murine herpes virus entry protein b, mhve poliovirus receptor homolog. Engineered: yes. Mutation: yes
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: pvrl2, mph, pvr, pvs. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek 293f.
Resolution:
3.25Å     R-factor:   0.250     R-free:   0.335
Authors: O.J.Harrison,J.Brasch,L.Shapiro
Key ref: O.J.Harrison et al. (2012). Nectin ectodomain structures reveal a canonical adhesive interface. Nat Struct Mol Biol, 19, 906-915. PubMed id: 22902367
Date:
26-Jun-12     Release date:   22-Aug-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P32507  (PVRL2_MOUSE) -  Poliovirus receptor-related protein 2
Seq:
Struc:
 
Seq:
Struc:
530 a.a.
218 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 

 
Nat Struct Mol Biol 19:906-915 (2012)
PubMed id: 22902367  
 
 
Nectin ectodomain structures reveal a canonical adhesive interface.
O.J.Harrison, J.Vendome, J.Brasch, X.Jin, S.Hong, P.S.Katsamba, G.Ahlsen, R.B.Troyanovsky, S.M.Troyanovsky, B.Honig, L.Shapiro.
 
  ABSTRACT  
 
No abstract given.