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PDBsum entry 4fkj

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protein ligands links
Transferase/transferase inhibitor PDB id
4fkj
Jmol
Contents
Protein chain
279 a.a.
Ligands
11K
ACT
Waters ×172
PDB id:
4fkj
Name: Transferase/transferase inhibitor
Title: Crystal structure of the cdk2 in complex with aminopyrazole
Structure: Cyclin-dependent kinase 2. Chain: a. Synonym: cell division protein kinase 2, p33 protein kinase engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdk2, cdkn2. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high-five.
Resolution:
1.63Å     R-factor:   0.181     R-free:   0.199
Authors: Y.N.Kang,J.A.Stuckey
Key ref: Y.N.Kang and j.a.stuckey Crystal structure of the cdk2 in complex with aminopy inhibitor. To be published, .
Date:
13-Jun-12     Release date:   08-May-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P24941  (CDK2_HUMAN) -  Cyclin-dependent kinase 2
Seq:
Struc:
298 a.a.
278 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.22  - Cyclin-dependent kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cyclin-dependent protein kinase holoenzyme complex   15 terms 
  Biological process     regulation of gene silencing   27 terms 
  Biochemical function     nucleotide binding     12 terms