spacer
spacer

PDBsum entry 4esl

Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Oxidoreductase PDB id
4esl
Jmol
Contents
Protein chains
529 a.a.
166 a.a.
31 a.a.
Ligands
HEM
HAS
OLC ×16
CUA
Metals
_CU
Waters ×78
Superseded by: 4gp8
PDB id:
4esl
Name: Oxidoreductase
Title: Structure of recombinant cytochrome ba3 oxidase mutant y133w from thermus thermophilus
Structure: CytochromE C oxidase subunit 1. Chain: a. Synonym: cytochromE C ba(3) subunit i, cytochromE C oxidase polypeptide i, cytochrome cba3 subunit 1. Engineered: yes. Mutation: yes. CytochromE C oxidase subunit 2. Chain: b. Synonym: cytochromE C ba(3) subunit ii, cytochromE C oxidas
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8 / atcc 27634 / dsm 579. Gene: cbaa, ttha1135. Expressed in: thermus thermophilus. Expression_system_taxid: 300852. Gene: cbab, ctac, ttha1134. Gene: cbad, ttha1133.
Resolution:
2.80Å     R-factor:   0.179     R-free:   0.227
Authors: Y.Li,Y.Chen,C.D.Stout
Date:
23-Apr-12     Release date:   02-May-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q5SJ79  (COX1_THET8) -  Cytochrome c oxidase subunit 1
Seq:
Struc:
 
Seq:
Struc:
562 a.a.
529 a.a.*
Protein chain
Pfam   ArchSchema ?
Q5SJ80  (COX2_THET8) -  Cytochrome c oxidase subunit 2
Seq:
Struc:
168 a.a.
166 a.a.
Protein chain
Pfam   ArchSchema ?
P82543  (COXA_THET8) -  Cytochrome c oxidase polypeptide 2A
Seq:
Struc:
34 a.a.
31 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains A, B, C: E.C.1.9.3.1  - Cytochrome-c oxidase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O
4 × ferrocytochrome c
Bound ligand (Het Group name = HEM)
matches with 63.64% similarity
+ O(2)
+ 4 × H(+)
= 4 × ferricytochrome c
+ 2 × H(2)O
      Cofactor: Cu cation
Molecule diagrams generated from .mol files obtained from the KEGG ftp site