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PDBsum entry 4duo

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protein ligands metals links
Isomerase/isomerase inhibitor PDB id
4duo
Jmol
Contents
Protein chain
388 a.a.
Ligands
XYL
Metals
_MG ×2
Waters ×228
PDB id:
4duo
Name: Isomerase/isomerase inhibitor
Title: Room-temperature x-ray structure of d-xylose isomerase in co 2mg2+ ions and xylitol at ph 7.7
Structure: Xylose isomerase. Chain: a. Ec: 5.3.1.5
Source: Streptomyces rubiginosus. Organism_taxid: 1929
Resolution:
2.00Å     R-factor:   0.148     R-free:   0.200
Authors: A.Y.Kovalevsky,L.Hanson,P.Langan
Key ref: A.Kovalevsky et al. (2012). Inhibition of D-xylose isomerase by polyols: atomic details by joint X-ray/neutron crystallography. Acta Crystallogr D Biol Crystallogr, 68, 1201-1206. PubMed id: 22948921
Date:
22-Feb-12     Release date:   29-Aug-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P24300  (XYLA_STRRU) -  Xylose isomerase
Seq:
Struc:
388 a.a.
388 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.5.3.1.5  - Xylose isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: D-xylopyranose = D-xylulose
D-xylopyranose
Bound ligand (Het Group name = XYL)
corresponds exactly
= D-xylulose
      Cofactor: Mg(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     carbohydrate metabolic process   3 terms 
  Biochemical function     isomerase activity     4 terms  

 

 
    Key reference    
 
 
Acta Crystallogr D Biol Crystallogr 68:1201-1206 (2012)
PubMed id: 22948921  
 
 
Inhibition of D-xylose isomerase by polyols: atomic details by joint X-ray/neutron crystallography.
A.Kovalevsky, B.L.Hanson, S.A.Mason, V.T.Forsyth, Z.Fisher, M.Mustyakimov, M.P.Blakeley, D.A.Keen, P.Langan.
 
  ABSTRACT  
 
No abstract given.