PDBsum entry 4dov

Replication

PDB id

4dov

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Contents

			Protein chains

					157 a.a.

			Waters ×240

PDB id:

4dov

Links

Name:

Replication

Title:

Structure of free mouse orc1 bah domain

Structure:

Origin recognition complex subunit 1. Chain: a, c. Fragment: bah domain (unp residues 9-170). Synonym: orc1. Engineered: yes

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: orc1, orc1l. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.70Å

R-factor:

0.216

R-free:

0.243

Authors:

J.Song,D.J.Patel

Key ref:

A.J.Kuo et al. (2012). The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome. Nature, 484, 115-119. PubMed id: 22398447

Date:

10-Feb-12

Release date:

07-Mar-12

PROCHECK

	Headers

	References

Protein chains

Q9Z1N2 (ORC1_MOUSE) - Origin recognition complex subunit 1 from Mus musculus

Seq: Struc:

Seq: Struc:					840 a.a. 157 a.a.

Key:

PfamA domain

Secondary structure

CATH domain

	Nature 484:115-119 (2012)
PubMed id: 22398447

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
A.J.Kuo, J.Song, P.Cheung, S.Ishibe-Murakami, S.Yamazoe, J.K.Chen, D.J.Patel, O.Gozani.

ABSTRACT

No abstract given.

Literature references that cite this PDB file's key reference

PubMed id

Reference

23211769

C.A.Musselman, M.E.Lalonde, J.Côté, and T.G.Kutateladze (2012).
Perceiving the epigenetic landscape through histone readers.

Nat Struct Mol Biol, 19, 1218-1227.

23022729

S.B.Rothbart, K.Krajewski, N.Nady, W.Tempel, S.Xue, A.I.Badeaux, D.Barsyte-Lovejoy, J.Y.Martinez, M.T.Bedford, S.M.Fuchs, C.H.Arrowsmith, and B.D.Strahl (2012).
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.

Nat Struct Mol Biol, 19, 1155-1160.

The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.