spacer
spacer

PDBsum entry 4b2q

Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Hydrolase PDB id
4b2q
Jmol
Contents
Protein chains
(+ 0 more) 485 a.a.
(+ 0 more) 470 a.a.
269 a.a.
132 a.a.
59 a.a.
(+ 14 more) 76 a.a.
129 a.a.
120 a.a.
65 a.a.
110 a.a.
Ligands
ATP ×6
ADP ×4
Metals
_MG ×10
PDB id:
4b2q
Name: Hydrolase
Title: Model of the yeast f1fo-atp synthase dimer based on subtomog average
Structure: Atp synthase subunit alpha, mitochondrial. Chain: a, c, a, c. Fragment: residues 61-545. Atp synthase subunit alpha, mitochondrial. Chain: b, b. Fragment: residues 60-545. Atp synthase subunit beta, mitochondrial. Chain: d, d. Fragment: residues 39-508.
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: d273-10b/a. Organ: mitochondria. Bos taurus. Cattle. Organism_taxid: 9913. Organ: mitochondria
Authors: K.M.Davies,W.Kuehlbrandt
Key ref: K.M.Davies et al. (2012). Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae. Proc Natl Acad Sci U S A, 109, 13602-13607. PubMed id: 22864911 DOI: 10.1073/pnas.1204593109
Date:
17-Jul-12     Release date:   29-Aug-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P07251  (ATPA_YEAST) -  ATP synthase subunit alpha, mitochondrial
Seq:
Struc:
 
Seq:
Struc:
545 a.a.
485 a.a.
Protein chains
Pfam   ArchSchema ?
P00830  (ATPB_YEAST) -  ATP synthase subunit beta, mitochondrial
Seq:
Struc:
511 a.a.
470 a.a.
Protein chains
Pfam   ArchSchema ?
P38077  (ATPG_YEAST) -  ATP synthase subunit gamma, mitochondrial
Seq:
Struc:
311 a.a.
269 a.a.
Protein chains
Pfam   ArchSchema ?
Q12165  (ATPD_YEAST) -  ATP synthase subunit delta, mitochondrial
Seq:
Struc:
160 a.a.
132 a.a.
Protein chains
Pfam   ArchSchema ?
P21306  (ATP5E_YEAST) -  ATP synthase subunit epsilon, mitochondrial
Seq:
Struc:
62 a.a.
59 a.a.
Protein chains
Pfam   ArchSchema ?
P61829  (ATP9_YEAST) -  ATP synthase subunit 9, mitochondrial
Seq:
Struc:
76 a.a.
76 a.a.
Protein chains
Pfam   ArchSchema ?
P13619  (AT5F1_BOVIN) -  ATP synthase F(0) complex subunit B1, mitochondrial
Seq:
Struc:
256 a.a.
129 a.a.
Protein chains
Pfam   ArchSchema ?
P13620  (ATP5H_BOVIN) -  ATP synthase subunit d, mitochondrial
Seq:
Struc:
161 a.a.
120 a.a.
Protein chains
Pfam   ArchSchema ?
P02721  (ATP5J_BOVIN) -  ATP synthase-coupling factor 6, mitochondrial
Seq:
Struc:
108 a.a.
65 a.a.
Protein chains
Pfam   ArchSchema ?
P13621  (ATPO_BOVIN) -  ATP synthase subunit O, mitochondrial
Seq:
Struc:
213 a.a.
110 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: Chains D, E, F, d, e, f: E.C.3.6.3.14  - H(+)-transporting two-sector ATPase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + H2O + H+(In) = ADP + phosphate + H+(Out)
ATP
Bound ligand (Het Group name = ATP)
corresponds exactly
+ H(2)O
+ H(+)(In)
= ADP
+ phosphate
+ H(+)(Out)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   15 terms 
  Biological process     transport   8 terms 
  Biochemical function     nucleotide binding     10 terms  

 

 
    reference    
 
 
DOI no: 10.1073/pnas.1204593109 Proc Natl Acad Sci U S A 109:13602-13607 (2012)
PubMed id: 22864911  
 
 
Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae.
K.M.Davies, C.Anselmi, I.Wittig, J.D.Faraldo-Gómez, W.Kühlbrandt.
 
  ABSTRACT  
 
No abstract given.