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PDBsum entry 4ai6

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protein ligands metals links
Motor protein PDB id
4ai6
Jmol
Contents
Protein chains
2650 a.a.
Ligands
ATP ×2
ADP ×4
SO4 ×2
Metals
_MG ×2
PDB id:
4ai6
Name: Motor protein
Title: Dynein motor domain - adp complex
Structure: Glutathione s-transferase class-mu 26 kda isozyme heavy chain cytoplasmic. Chain: a, b. Fragment: residues 1-218,1364-3038,3292-4092. Synonym: gst 26, sj26 antigen, sjgst, dyhc. Engineered: yes
Source: Schistosoma japonicum, saccharomyces cerevisiae. Organism_taxid: 6182, 4932. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Resolution:
3.40Å     R-factor:   0.244     R-free:   0.303
Authors: H.Schmidt,E.S.Gleave,A.P.Carter
Key ref: H.Schmidt et al. (2012). Insights into dynein motor domain function from a 3.3-Å crystal structure. Nat Struct Mol Biol, 19, 492. PubMed id: 22426545
Date:
08-Feb-12     Release date:   14-Mar-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P08515  (GST26_SCHJA) -  Glutathione S-transferase class-mu 26 kDa isozyme
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
218 a.a.
2650 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.5.1.18  - Glutathione transferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: RX + glutathione = HX + R-S-glutathione
RX
+ glutathione
= HX
+ R-S-glutathione
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     axonemal dynein complex   2 terms 
  Biological process     microtubule-based movement   2 terms 
  Biochemical function     nucleotide binding     5 terms  

 

 
    reference    
 
 
Nat Struct Mol Biol 19:492 (2012)
PubMed id: 22426545  
 
 
Insights into dynein motor domain function from a 3.3-Å crystal structure.
H.Schmidt, E.S.Gleave, A.P.Carter.
 
  ABSTRACT  
 
No abstract given.