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PDBsum entry 4a3q

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protein ligands Protein-protein interface(s) links
Isomerase PDB id
4a3q
Jmol
Contents
Protein chains
356 a.a.
Ligands
PLP ×2
SO4 ×13
ACT ×2
Waters ×266
PDB id:
4a3q
Name: Isomerase
Title: The 2.15 angstrom resolution crystal structure of staphyloco aureus alanine racemase
Structure: Alanine racemase 1. Chain: a, b. Engineered: yes
Source: Staphylococcus aureus. Organism_taxid: 1280. Strain: mu50. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss.
Resolution:
2.15Å     R-factor:   0.190     R-free:   0.236
Authors: E.R.Scaletti,S.R.Luckner,K.L.Krause
Key ref: E.R.Scaletti et al. (2012). Structural features and kinetic characterization of alanine racemase from Staphylococcus aureus (Mu50). Acta Crystallogr D Biol Crystallogr, 68, 82-92. PubMed id: 22194336
Date:
04-Oct-11     Release date:   28-Dec-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P63479  (ALR1_STAAM) -  Alanine racemase 1
Seq:
Struc:
382 a.a.
356 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.5.1.1.1  - Alanine racemase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-alanine = D-alanine
L-alanine
Bound ligand (Het Group name = ACT)
matches with 66.67% similarity
= D-alanine
      Cofactor: Pyridoxal 5'-phosphate
Pyridoxal 5'-phosphate
Bound ligand (Het Group name = PLP) matches with 93.75% similarity
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     alanine metabolic process   2 terms 
  Biochemical function     catalytic activity     4 terms  

 

 
    reference    
 
 
Acta Crystallogr D Biol Crystallogr 68:82-92 (2012)
PubMed id: 22194336  
 
 
Structural features and kinetic characterization of alanine racemase from Staphylococcus aureus (Mu50).
E.R.Scaletti, S.R.Luckner, K.L.Krause.
 
  ABSTRACT  
 
No abstract given.