PDBsum entry 4a2c

Oxidoreductase

PDB id

4a2c

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Contents

			Protein chains

					346 a.a.

			Metals

					_ZN ×2


					_NI ×3

			Waters ×608

PDB id:

4a2c

Links

Name:

Oxidoreductase

Title:

Crystal structure of galactitol-1-phosphate dehydrogenase from escherichia coli

Structure:

Galactitol-1-phosphate 5-dehydrogenase. Chain: a, b. Synonym: galactitol-1-phosphate dehydrogenase. Engineered: yes

Source:

Escherichia coli. Organism_taxid: 83333. Strain: k-12. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.87Å

R-factor:

0.216

R-free:

0.273

Authors:

Y.Alvarez,M.Esteban-Torres,I.Acebron,B.De Las Rivas,R.Munoz, J.M.Mancheno

Key ref:

M.Esteban-Torres et al. (2012). The crystal structure of galactitol-1-phosphate 5-dehydrogenase from Escherichia coli K12 provides insights into its anomalous behavior on IMAC processes. Febs Lett, 586, 3127-3133. PubMed id: 22979983

Date:

26-Sep-11

Release date:

08-Aug-12

PROCHECK

	Headers

	References

Protein chains

P0A9S3 (GATD_ECOLI) - Galactitol 1-phosphate 5-dehydrogenase from Escherichia coli (strain K12)

Seq: Struc:					346 a.a. 346 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.1.1.1.251 - galactitol-1-phosphate 5-dehydrogenase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

galactitol 1-phosphate + NAD⁺ = keto-D-tagatose 6-phosphate + NADH + H⁺

galactitol 1-phosphate	+	NAD(+)	=	keto-D-tagatose 6-phosphate	+	NADH	+	H(+)

Cofactor:

Zn(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

	Febs Lett 586:3127-3133 (2012)
PubMed id: 22979983

The crystal structure of galactitol-1-phosphate 5-dehydrogenase from Escherichia coli K12 provides insights into its anomalous behavior on IMAC processes.
M.Esteban-Torres, Y.Alvarez, I.Acebrón, B.de las Rivas, R.Muñoz, G.W.Kohring, A.M.Roa, M.Sobrino, J.M.Mancheño.

ABSTRACT

No abstract given.