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PDBsum entry 3zfl

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protein links
Transferase PDB id
3zfl
Jmol
Contents
Protein chain
208 a.a.
Waters ×349
PDB id:
3zfl
Name: Transferase
Title: Crystal structure of the v58a mutant of human class alpha glutathione transferase in the apo form
Structure: Glutathione s-transferase a1. Chain: a, b. Synonym: gst ha subunit 1, gst class-alpha member 1, gst-ep gsta1-1, gth1, glutathione transferase. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Organ: liver. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss.
Resolution:
1.88Å     R-factor:   0.221     R-free:   0.289
Authors: N.Parbhoo,S.Fanucchi,I.A.Achilonu,M.A.Fernandes,S.Gildenhuys H.W.Dirr
Key ref: N.Parbhoo et al. Crystal structure of the V58a mutant of human class a glutathione transferase in the apo form. To be published, .
Date:
12-Dec-12     Release date:   19-Dec-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P08263  (GSTA1_HUMAN) -  Glutathione S-transferase A1
Seq:
Struc:
222 a.a.
208 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.5.1.18  - Glutathione transferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: RX + glutathione = HX + R-S-glutathione
RX
+ glutathione
= HX
+ R-S-glutathione
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   3 terms 
  Biological process     metabolic process   6 terms 
  Biochemical function     transferase activity     2 terms